Effects of new wound dressings on healing of thermal burns of the skin in acute radiation disease

Legeza, V I; Galenko-Yaroshevskii, V. P.; Zinoviev, E. V.; Paramonov, B. A.; Kreichman, G. S.; Turkovskii, I. I.; Gumenyuk, S. E.; Karnovich, A. G.; Хрипунов, А. К.

doi:10.1007/bf02694188

Cited by 12 publications

(11 citation statements)

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“…Owing to its biocompatibility, BC has also recently attracted a great deal of attention for biomedical applications. For instance, BC has been successfully used as artificial skin for burn or wound healing material (Fontana et al 1990;Ciechanska et al 1998;Czaja et al 2006;Alvarez et al 2004;Legeza et al 2004), artificial blood vessels for microsurgery (Klemm et al 1999(Klemm et al , 2001. The potential of BC scaffold for in vitro and in vivo tissue regeneration also continues to be explored and shows great promise (Watanabe et al 1993;Svensson et al 2005;Helenius et al 2006;Backdahl et al 2006).…”

Section: Introductionmentioning

confidence: 94%

Bacterial cellulose/poly(ethylene glycol) composite: characterization and first evaluation of biocompatibility

2009

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Bacterial cellulose (BC)/poly(ethylene glycol) (PEG) composite was prepared by immersing wet BC pellicle in PEG aqueous solution followed by freeze-drying process. The product looks like a foam structure. The morphology of BC/PEG composite was examined by scanning electron microscope (SEM) and compared with pristine BC. SEM images showed that PEG molecules was not only coated on the BC fibrils surface but also penetrated into BC fiber networks. It has very well interconnected porous network structure and large aspect surface. The composite was also characterized by Fourier transform infrared spectrum, X-ray diffraction, thermogravimetric analysis (TGA) and tensile test. It was found that the presence of PEG affected the preferential orientation of the (1 " 10) plane during the drying process of BC pellicle, which in turn decrease the crystallinity of dried BC. The TGA result showed that the thermal stability was improved from 263 to 293°C, which might be associated with strong interaction between BC and PEG. Tensile test results indicate that the Young's modulus and tensile strength tend to decrease. Biocompatibility of composite was preliminarily evaluated by cell adhesion studies using 3T3 fibroblast cells. The cells incubated with BC/PEG scaffolds for 48 h were capable of forming cell adhesion and proliferation, which showed much better biocompatibility than the pure BC. The prepared BC/PEG scaffolds can be used for wound dressing or tissue-engineering scaffolds.

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Section: Introductionmentioning

confidence: 94%

Bacterial cellulose/poly(ethylene glycol) composite: characterization and first evaluation of biocompatibility

2009

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“…They obtained bio-polymer film by supplementing 30% (v/v) of aloe gel in the BC culture medium which outcomes BC reinforced fibers with improved properties in terms of mechanical strength, crystallinity, water absorption capacity, and water vapor permeability in comparison with unmodified BC films. Legeza et al (2004) produced a BC wound dressing for the treatment of third degree burns that is impregnated with superoxide dismutase (an antioxidant) or poviargol (an antibiotic). Further, BC composite with kaolin (a blood clotting agent) was proved to be a wound healing material as much in a short term as long term (Wanna, Alam, Toivola, & Alam, 2013).…”

Section: Wound Dressingsmentioning

confidence: 99%

A multipurpose natural and renewable polymer in medical applications: Bacterial cellulose

Barud

Silva

Barud

et al. 2016

Carbohydrate Polymers

290

133

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Bacterial cellulose (BC) produced by some bacteria, among them Gluconacetobacter xylinum, which secrets an abundant 3D networks fibrils, represents an interesting emerging biocompatible nanomaterial. Since its discovery BC has shown tremendous potential in a wide range of biomedical applications, such as artificial skin, artificial blood vessels and microvessels, wound dressing, among others. BC can be easily manipulated to improve its properties and/or functionalities resulting in several BC based nanocomposites. As example BC/collagen, BC/gelatin, BC/Fibroin, BC/Chitosan, etc. Thus, the aim of this review is to discuss about the applicability in biomedicine by demonstrating a variety of forms of this biopolymer highlighting in detail some qualities of bacterial cellulose. Therefore, various biomedical applications ranging from implants and scaffolds, carriers for drug delivery, wound-dressing materials, etc. that were reported until date will be presented.

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“…Biomedical application include the use of BC for the production of contact lenses, electroconductive composite hydrogels biosensors, membranes for topical delivery of lidocaine and dietary supplements for combating diabetes, wound dressings, artificial skins and biomembranes [17,[47][48][49][50]. MC membranes can also be infused with compounds that are known to promote healing, for example, superoxide dismutase (antioxidant), poviargol (antibiotic) [52]. Wan et al [53] create a microbial cellulose membrane coated with hydroxyapatite (HAp), HAp-BC nanocomposites are important for applications as artificial bones and scaffolds for tissue engineering.…”

Section: Medical Applicationsmentioning

confidence: 99%

Structure, Properties and Medical Advances for Biocellulose Applications: A Review

Mohammedi¹

2017

AJPST

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Microbial exopolysaccharides (EPS) obtained from microbial sources, became simply available for a broad range of applications, especially for medicine and pharmaceutical industries. One of these EPS bacterial cellulose known as biocellulose (BC). BC is a pure extracellular cellulose, which accumulate outside the cells, produced by several species of microorganisms, like Gluconacetobacter; Achromobacter; Sarcina and Agrobacterium with a great number of applications. It is an organic unbranched polysaccharide, type β-1,4-glucan, composed of glucopyranose residues. Biocellulose is used as artificial skin and occlusive dressings to treat chronic wounds and to heal burns, in microsurgeries as artificial blood vessels, scaffolds in tissue engineering and many other applications. This work represents a review on this remarkably microbial biomaterial and thus an update of a collection of scientific data from original research between 1979 and 2016. The paper started on structural, composition, properties and characterization and biogenesis of this biopolymer, then it gives a synthesis on a variety of biomedical applications.

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Effects of new wound dressings on healing of thermal burns of the skin in acute radiation disease

Cited by 12 publications

References 1 publication

Bacterial cellulose/poly(ethylene glycol) composite: characterization and first evaluation of biocompatibility

Bacterial cellulose/poly(ethylene glycol) composite: characterization and first evaluation of biocompatibility

A multipurpose natural and renewable polymer in medical applications: Bacterial cellulose

Structure, Properties and Medical Advances for Biocellulose Applications: A Review

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