Effects of nifedipine on left ventricular distensibility, relaxation and filling dynamics during pacing-induced myocardial ischemia

Summary: To determine whether ajmaline (A) can be safely applied in coronary artery disease (CAD), changes of left ventricular (LV) function after acute ajmaline application were analyzed by pulsed Doppler echocardiography in 10 CAD patients. LV pressures in systole and end-diastole and LVEF remained normal and comparable. Doppler normalized peak filling rate (p<0.02), peak early/atrial filling velocity (E/A) ratio (peO.01) and Edeceleration (pe0.05) increased. The increase in E/A and in E-deceleration relative to base values was directly correlated (p

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Improved diastolic LV filling after acute application of ajmaline in patients with coronary artery disease and normal systolic LV function

Jing

Thormann

Mitrović

et al. 1990

Clinical Cardiology

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Amlodipine in patients with stable angina pectoris treated with nitrates and beta-blockers. The influence on exercise tolerance, systolic and diastolic functions of the left ventricle

Meluzı́n

Stejfa

Novák

et al. 1992

International Journal of Cardiology

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Variability of changes in Doppler transmitral filling pattern during stress echocardiography in patients with stable angina pectoris

Meluzı́n¹,

Toman²,

Souček³

et al. 1994

International Journal of Cardiology

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Effects of nifedipine on left ventricular distensibility, relaxation and filling dynamics during pacing-induced myocardial ischemia

Cited by 3 publications

References 21 publications

Improved diastolic LV filling after acute application of ajmaline in patients with coronary artery disease and normal systolic LV function

Improved diastolic LV filling after acute application of ajmaline in patients with coronary artery disease and normal systolic LV function

Amlodipine in patients with stable angina pectoris treated with nitrates and beta-blockers. The influence on exercise tolerance, systolic and diastolic functions of the left ventricle

Variability of changes in Doppler transmitral filling pattern during stress echocardiography in patients with stable angina pectoris

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