Effects of Nut Consumption on Cardiovascular Risk Factors and Coronary Heart Diseases

Zibaeenezhad, Mohammad Javad; Elyaspour, Zahra

doi:10.31989/ffhd.v12i11.1022

Cited by 2 publications

(1 citation statement)

References 84 publications

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“…Serenoa repens, commonly known as the American dwarf saw palmetto plant, contains bioactive compounds, including phytosterols, fatty acids, and their ethyl esters, which have been identified as beneficial against cardiovascular risk factors [12]. These compounds are derived from the plant's dried fruits [13].…”

Section: Ffhdmentioning

confidence: 99%

Clinical effect of phytosterol-enriched saw palmetto extract on urinary function in healthy middle-aged and older males: a double-blind, placebo-controlled randomized comparative study

Hisajima,

Waki,

Suzuki

et al. 2024

FFHD

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Background: Saw palmetto extract (SPE) is one of the most widely used supplements for benign prostatic hyperplasia (BPH) due to its pharmacological effects. β-sitosterol-enriched saw palmetto oil (VISPO™) contains more than 3% β-sitosterol and 85% total fatty acids and has been shown to improve symptoms in patients with BPH. Lower urinary tract symptoms (LUTS) require primary preventive measures in countries with accelerated population aging, including Japan. VISPO™ is expected to be effective against the early symptoms of LUTS. However, the effect of VISPO™ on urinary function in healthy individuals has not been elucidated. Objective: This clinical study evaluated the efficacy and tolerability of VISPO™ in the management of urinary complaints among healthy middle-aged and older men who did not require treatment. Methods: We conducted a randomized, double-blind, placebo-controlled trial that included 54 male participants who were assigned to consume VISPO™ or placebo (olive oil) capsules for 12 weeks. Biometric data, uroflowmetry results, and salivary hormone levels were assessed at weeks 1 and 12. Urinary function and quality of life were assessed at weeks 1, 4, 8, and 12 using the International Prostate Symptom Score (IPSS), Overactive Bladder Symptom Score (OABSS), Core Lower Urinary Tract Symptom Score (CLSS), and WHOQOL-26. Results: Two-way analysis of variance revealed that IPSS and OABSS were significantly lower in the VISPO™ group that in the placebo group. However, there were no significant differences in urine volume, urinary flow rate, or salivary hormone levels. In addition, no participants reported adverse effects (diarrhea, abdominal pain, etc.). Conclusion: The results of the present study, which is the first randomized controlled trial of VISPO™ conducted among healthy participants, demonstrate the effectiveness of VISPO™ in the management of lower urinary tract complaints that do not require treatment. Trial Registration: University Hospital Medical Information Network Clinical Trials Registry (UMIN000046386). Keywords: saw palmetto, VISPO™, β-sitosterol, fatty acids, healthy subjects, primary preventive, IPSS, OABSS, lower urinary tract symptoms (LUTS)

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Section: Ffhdmentioning

confidence: 99%

Clinical effect of phytosterol-enriched saw palmetto extract on urinary function in healthy middle-aged and older males: a double-blind, placebo-controlled randomized comparative study

Hisajima,

Waki,

Suzuki

et al. 2024

FFHD

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Recent Innovations on the Reuse of Almond and Hazelnut By-Products: A Review

Ollani,

Peano,

Sottile

2024

Sustainability

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Nuts consumption has increased significantly in the last 10 years, especially driven by the stimulated awareness of their possible beneficial health effects. Increased nuts consumption is linked to an obvious accumulation of by-products and waste. With the view of the circular economy, the aim of this review is to analyse the recent and innovative approaches able to valorise the by-products derived from almonds and hazelnuts, two important nut products of the Italian scene, with historical and traditional importance. The most important solutions are concerned with reuse of almond hull, shell, skin, oil cake, and hazelnut shell; skin and oil cake are often considered waste or by-products. Many interesting implications in the feed and food sectors have been detected in the last ten years, aimed at designing innovative materials developed from by-products and extraction of bioactive molecules for different purposes. The perspective chosen to discuss the topic is related to the sustainability of these processes, in terms of both the environment and economy. The circular economy supports a zero-waste approach, which should not also be meant as a zero-cost process in terms of the level of technology that has been partially developed.

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Effects of Nut Consumption on Cardiovascular Risk Factors and Coronary Heart Diseases

Cited by 2 publications

References 84 publications

Clinical effect of phytosterol-enriched saw palmetto extract on urinary function in healthy middle-aged and older males: a double-blind, placebo-controlled randomized comparative study

Clinical effect of phytosterol-enriched saw palmetto extract on urinary function in healthy middle-aged and older males: a double-blind, placebo-controlled randomized comparative study

Recent Innovations on the Reuse of Almond and Hazelnut By-Products: A Review

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