1988
DOI: 10.1183/09031936.93.01060505
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Effects of oral steroids on immunoglobulins in bronchoalveolar lavage fluid in active sarcoidosis

Abstract: Immunoglobulin (Ig) levels increase in the lower respiratory tract of patients with pulmonary sarcoidosis. We evaluated the effects of prednisone therapy upon Ig concentrations in bronchoalveolar lavage (BAL) fluid of ten patients with active disease (greater than 30% T-lymphocytes in BAL and positive 67Gallium (67Ga) lung scan). Therapy significantly lowered T-lymphocyte percentages in BAL and 67Ga lung scan indices and was followed by a slight improvement of the studied functional parameters. Biochemical ana… Show more

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