The two-phase closed thermosyphon (TPCT), which is essentially a gravity-assisted wickless heat pipe, utilizes the evaporation and condensation of the working fluid inside the TPCT to transport heat. This experimental study was carried out to understand the thermal performance of circular finned thermosyphon using nanofluid with alcohol and was analyzed, compared with alcohol and base fluid DI water. The concentration of nanoparticle used in this setup was 110mg/lit of TiO2combined with 0.2 ml of ethylene glycol. The heat input (Q) were 10W, 12W, 14 W and 16 W and the orientation 30°, 45°, 60° and 90°.The results demonstrate that TiO2nanofluid with 0.2 ml of ethylene glycol improves the performance through reduction in thermal resistance by 85.86%.