Effects of Orlistat on Visceral Fat After Liposuction

Montoya, Teresa; Monereo, Susana; Olivar, Juana; Iglesias, Paloma; Díaz, P.

doi:10.1111/j.1524-4725.2009.01072.x

Cited by 14 publications

(8 citation statements)

References 30 publications

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“…Last but not the least, reviewing the literature we identified studies, which could have been included, at least at the systematic review, such as those from Robles-Cervantes et al to Montoya et al which fulfill the inclusion criteria described herein [4,5]. This fact seems to limit the validity and reliability of the review, and thus its results.…”

mentioning

confidence: 95%

Metabolic Effects of Large-Volume Liposuction for Obese Healthy Women: A Meta-analysis of Fasting Insulin Levels

Seretis

Demiri

2015

Aesth Plast Surg

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confidence: 95%

Metabolic Effects of Large-Volume Liposuction for Obese Healthy Women: A Meta-analysis of Fasting Insulin Levels

Seretis

Demiri

2015

Aesth Plast Surg

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“…Based on the idea that visceral fat has deleterious effects on metabolism, surgical removal of visceral fat was proposed to be a way forward in achieving lower visceral adiposity. However, removal of visceral fat alone does not provide metabolic advantages2728, possibly because visceral fat is highly mobilized. Although fat transplantation involving donor and recipient mice has been carried out earlier324, we raised the question: Does autologous transplantation of visceral fat to sub-cutaneous region offer metabolic advantage?…”

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confidence: 99%

Location, location, location: Beneficial effects of autologous fat transplantation

Satoor

Puranik

Kumar

et al. 2011

Sci Rep

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Visceral adiposity is a risk factor for cardiovascular disorders, type 2 diabetes mellitus (T2D) and associated metabolic diseases. Sub-cutaneous fat is believed to be intrinsically different from visceral fat. To understand molecular mechanisms involved in metabolic advantages of fat transplantation, we studied a rat model of diet-induced adiposity. Adipokine genes (Adiponectin, Leptin, Resistin and Visfatin) were expressed at 10,000 to a million-fold lower in visceral fat depot as compared to peripheral (thigh/chest) fat depots. Interestingly, autologous transplantation of visceral fat to subcutaneous sites resulted in increased gene transcript abundance in the grafts by 3 weeks post-transplantation, indicating the impact of local (residence) factors influencing epigenetic memory. We show here that active transcriptional state of adipokine genes is linked with glucose mediated recruitment of enzymes that regulate histone methylation. Adipose depots have “residence memory” and autologous transplantation of visceral fat to sub-cutaneous sites offers metabolic advantage.

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“…Otherwise, a stable nutritional biochemical pattern was documented throughout the observation period (Table 2). Table 3 summarizes the findings from the literature concerning the impact of liposuction and abdominoplasty on metabolic variables [2][3][4][5][6][7][8][9][10][11][12].…”

Section: Resultsmentioning

confidence: 99%

“…Alleviation of systemic inflammation and insulin resistance has been reported by some researches, whereas in certain studies, the improvement of plasma lipids has been confirmed [4][5][6][7][8]. In contrast, no changes in insulin action and cardiovascular risk factors have been noticed by other studies [9,10].…”

Section: Introductionmentioning

confidence: 85%

C-Reactive Protein Decrease After Postbariatric Abdominoplasty

Junior¹,

Modolin²,

Faintuch

et al. 2011

Inflammation

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In a prospective study, indices of glucose homeostasis, lipid profile, and systemic inflammation were monitored after an aesthetic abdominoplasty, aiming to scrutinize the possible metabolic benefits for abdominal fat removal. Premenopausal females with substantial weight loss (N=40) undergoing circumferential abdominoplasty (index group, n=20) or augmentation mammoplasty with mastopexy (controls, n=20) were recruited. All of them originally underwent Roux-en-Y gastric bypass. Variables included BMI, white blood cell count, C-reactive protein, hemoglobin, total cholesterol and fractions, triglycerides, glucose, and HbA1c. Follow-up reached 20.3 ± 13.6 months for index cases and 29.5 ± 17.4 months for controls. The metabolic and inflammatory indices improved after the bariatric surgery. Subsequent monitoring indicated a stable body weight and biochemical profile in both groups. The exceptions were HDL cholesterol and C-reactive protein, which respectively increased and diminished after the abdominoplasty, consistent with an inflammatory and metabolic advantage for this operation. This is the first long-term study in a weight-stable population to point out such a pattern after abdominoplasty.

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Effects of Orlistat on Visceral Fat After Liposuction

Abstract: Visceral fat does not decrease despite weight loss after liposuction. Orlistat use postliposuction might be a useful tool because it shows a tendency to reduce visceral fat and improve blood lipids profile.

Cited by 14 publications

References 30 publications

Metabolic Effects of Large-Volume Liposuction for Obese Healthy Women: A Meta-analysis of Fasting Insulin Levels

Metabolic Effects of Large-Volume Liposuction for Obese Healthy Women: A Meta-analysis of Fasting Insulin Levels

Location, location, location: Beneficial effects of autologous fat transplantation

C-Reactive Protein Decrease After Postbariatric Abdominoplasty

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