Effects of percutaneous vertebroplasty on respiratory parameters in patients with osteoporotic vertebral compression fractures

Abstract

Background: Vertebral compression fractures (VCFs) often occur in patients with osteoporosis. These fractures can also lead to postural changes. Several studies have shown that patients with vertebral compression fractures have a restrictive pattern in their pulmonary function. Percutaneous vertebroplasty (PVP) is the standard treatment for vertebral compression fractures, with the benefits of pain relief and enhancement of vertebral stability for partially collapsed vertebral bodies. However, the effects of PVP on short-term recovery of respiratory performance have not been investigated. Therefore, this study aimed to investigate the changes in pulmonary function, respiratory muscle strength, maximal voluntary ventilation (MVV), and chest mobility in patients with vertebral compression fractures after PVP. Methods: This research was approved by the clinic committee of the E-DA Hospital Institutional Review Board (EMRP07109N) and registered in the Thai Clinical Trials Registry (TCTR20211029005). We recruited 32 VCF patients. Four-time points were measured: before and after PVP and 1 and 3 weeks after PVP. We measured pulmonary function and maximum voluntary ventilation (MVV) by using spirometry. Respiratory muscle strength was assessed by using a respiratory pressure meter. The chest expansion test was used to evaluate chest mobility. A visual analogue scale (VAS) was used to assess resting and aggravated back pain. Results: Chest expansion and back pain improved at each time point after PVP. MVV showed significant progress at both 1 and 3 weeks after discharge. Forced expiratory volume in 1 second (FEV1) and maximal inspiratory muscle strength significantly improved 1 week after discharge. Conclusion: Taking all the data together, PVP not only can resolve severe back pain but can also provide excellent improvements in MVV and chest mobility in patients with vertebral compression fractures.

Innovative minimally invasive implants for osteoporosis vertebral compression fractures

“…The number of patients with osteoporosis vertebral compression fractures (OVCFs) is concurrently increasing, with the main symptoms being lower back pain and spinal deformity ( 2 ). In additon, OVCFs patients are predisposed to multiple comorbidities, including pulmonary dysfunction, bladder contraction disorder, weight loss, anxiety and depression ( 3 , 4 ). Furthermore, neurological impairments is also detected in OVCFs patients.…”

Percutaneous Curved Vertebroplasty and Bilateral-Pedicle-Approach Percutaneous Vertebroplasty in the Treatment of Osteoporotic Vertebral Compression Fracture: A Meta-Analysis

“…4 PVP is a standard treatment for fractures of the vertebral column, resulting in pain relief and improved stability. 5 Transpedicular puncture can be performed unilaterally or bilaterally during PVP. Although the former has the disadvantage of uneven distribution of bone cement, 6 it is clearly superior to the latter in terms of operation time, trauma, and radiation exposure to the doctors and patients.…”

Vertebra Segmentation Based Vertebral Compression Fracture Determination from Reconstructed Spine X-Ray Images

“…The treatments are generally indicated if the actual vertebral height loss is estimated above 40% and kyphosis as above 30 degrees. A deformity of vertebral bodies analysed on lateral spine imaging possess to be common difficulties of Osteoporosis that frequently leads to spinal deformity, back pain, functional inability and every tends to death [8][9]. Hence, they are considered as one of the most threatening diseases which maximizes the economic society burden [10].…”