Effects of Periodontal Therapy During Pregnancy on Periodontal Status, Biologic Parameters, and Pregnancy Outcomes: A Pilot Study

Abstract

Results from this pilot study (67 subjects) provide further evidence supporting the potential benefits of periodontal treatment on pregnancy outcomes. Treatment was safe, improved periodontal health, and prevented periodontal disease progression. Preliminary data show a 3.8-fold reduction in the rate of preterm delivery, a decrease in periodontal pathogen load, and a decrease in both GCF IL-1beta and serum markers of IL-6 response. However, further studies will be needed to substantiate these early findings.

Comparison of Serum Lipid and Thyroid Profiles Before and After Scaling and Root Planning in Periodontitis Subjects

“…The effect of periodontal therapy on PPD was observed to be very highly significant statistically (p<0.005) on comparison between day 0 and day 90. Similar results on PPD following periodontal therapy were observed previously by various investigators (Table 1) [15][16][17][18][19].…”

Periodontal diseases as an emerging potential risk factor for adverse pregnancy outcomes: A review of concepts

“…In contrast, López et al observed a significant reduction in the rate of preterm births and/or low birth weight in women that had received periodontal treatment before the 28 th gestation week when compared with women who had not received any treatment (26). Later in a pilot study by Offenbacher et al (2006), it was observed that periodontal treatment significantly reduced the incidence of preterm births, in spite of the small size of the sample (53 women) (27). Therefore, large scale longitudinal epidemiological and intervention studies are necessary to validate the causal relationship of periodontal diseases to adverse pregnancy outcomes.…”

Modern Approach to the Identification and Elimination of Periodontal Infection

“…As an example, many studies concerning preterm delivery and periodontitis have suggested mandatory periodontal treatment among pregnant women in order to prevent undesirable effects on the foetus [3][4][5][6]. Individual types of periopathogens have been directly connected with atherosclerosis, and their presence has been noted in atheromatous plaques in blood vessels [7].…”