Effects of personalized transcranial alternating current stimulation associated with physical therapy on motor and cognitive functions in people with Parkinson's disease

Castiglia, Leonora; Formaggio, Emanuela; Tenconi, Elena; Gallo, Laura; Tonellato, Michele; Masiero, Stefano; Felice, Alessandra Del

doi:10.1016/j.rehab.2018.05.592

Cited by 1 publication

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“…The ability to monitor the actual impact of the stimulation on targeted neuronal circuits would be of great value, not only for basic science but also in the applied medical fields. In the clinical context, there is an emerging interest in tACS as a supportive treatment of various mental (Klimke et al, 2016;Elyamany et al, 2020;Kayarian et al, 2020) and movement (Krause et al, 2014;Castiglia et al, 2018;Felice et al, 2019;Guerra et al, 2020) disorders. While general guidelines for the application of electrical stimulations have been proposed (Antal et al, 2017;Lefaucheur et al, 2017), one should keep in mind that, in clinical settings, simple EEG protocols and robust analysis procedures, such as the one presented in this paper are to be preferred.…”

Section: Discussionmentioning

confidence: 99%

Investigating Nuisance Effects Induced in EEG During tACS Application

Holzmann

Koppehele-Gossel

Voss

et al. 2021

Front. Hum. Neurosci.

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Transcranial alternating-current stimulation (tACS) in the frequency range of 1–100 Hz has come to be used routinely in electroencephalogram (EEG) studies of brain function through entrainment of neuronal oscillations. It turned out, however, to be highly non-trivial to remove the strong stimulation signal, including its harmonic and non-harmonic distortions, as well as various induced higher-order artifacts from the EEG data recorded during the stimulation. In this paper, we discuss some of the problems encountered and present methodological approaches aimed at overcoming them. To illustrate the mechanisms of artifact induction and the proposed removal strategies, we use data obtained with the help of a schematic demonstrator setup as well as human-subject data.

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