Effects of Physical Activity Levels on Fatigue Perception in Patients with Parkinson’s Disease and Neurologically Healthy Individuals

Santos, Paulo Cezar Rocha dos; Barbieri, Fábio Augusto; Orcioli‐Silva, Diego; Simieli, Lucas; Gobbi, Lílian Teresa Bucken

doi:10.4236/health.2014.621331

Cited by 6 publications

(6 citation statements)

References 29 publications

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“…The lack of change in step width of the PD group may suggest a robust system in patients with PD due to the difficulty in performing an adjustment -stiffness strategy [22]. Furthermore, patients with PD present a degradation in sensorimotor integration and sensory feedback [25,26], which may be associated with deficits in perception of fatigue [2,24] and consequently gait adjustments to improve safety. Another alternative explanation for the less pronounced changes in patients with PD may be that the central activation of their muscles in the fatigue protocol was insufficient to cause muscle overload and induce metabolic fatigue [5].…”

Section: Discussionmentioning

confidence: 99%

“…The general increase in human life expectancy coincides with an increase in the number of people with chronic diseases, such as Parkinson's disease (PD). Patients with PD present several motor and non-motor impairments [1], including a higher perception of fatigue than age-matched controls [2]. The exacerbated perception of fatigue is caused by musculoskeletal and neurophysiological impairments associated with PD, particularly resulting from altered norepinephrine and serotonin production due to degeneration of neurons of the raphe nuclei and locus coeruleus [1,3].…”

Section: Introductionmentioning

confidence: 99%

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Effects of leg muscle fatigue on gait in patients with Parkinson's disease and controls with high and low levels of daily physical activity

et al. 2016

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Patients with Parkinson's disease (PD) are more susceptible to muscle fatigue, which can damage their gait. Physical activity can improve muscle condition, which is an important aspect during walking. The aim of this study was to analyze the effects of lower limb muscle fatigue on gait in patients with PD and healthy individuals, grouped according to physical activity level. Twenty Patients with PD (PD group) and 20 matched individuals (control group) were distributed according to physical activity level into four subgroups of ten individuals (active and inactive). Participants performed three walking trials before and after lower limb muscle fatigue, induced by a repeated sit-to-stand task on a chair. Kinematic (stride length, width, duration, velocity and percentage of time in double support) and kinetic (propulsive and breaking anterior-posterior and medio-lateral impulse) gait parameters were analyzed. In both groups, participants increased stride length and velocity and decreased stride duration and braking vertical impulse after lower limb muscle fatigue. The PD groups presented higher step width and percentage of double time support than the control groups before muscle fatigue. The control groups increased step width and decreased percentage of time in double support, while the PD groups did not change these parameters. For physical activity level, active individuals presented longer stride length, greater stride velocity, higher braking and propulsive anterior-posterior impulse and shorter step width than inactive individuals. Groups sought more balance and safety after lower limb muscle fatigue. Physical activity level does not appear to modify the effects of lower limb muscle fatigue during unobstructed walking in individuals with PD or controls.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Effects of leg muscle fatigue on gait in patients with Parkinson's disease and controls with high and low levels of daily physical activity

et al. 2016

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“…Our results suggest that impairments in motor control and degradation in sensorimotor integration and sensory feedback presented by people with PD [42] have no effects on the role of muscle fatigue and lower limb muscle strength parameters. However, we need to consider the reduced time that the people with PD performed the muscle fatigue protocol, which could have been caused by exacerbated fatigue perception of people with PD [43] and maybe insufficient to cause muscle overload and induce metabolic fatigue [11], even with a reduction in muscle strength. Therefore, the interesting findings regarding lower limb muscle strength and effects of muscle fatigue seem to be important for prescription and monitoring of physical exercise for this population.…”

Section: Discussionmentioning

confidence: 99%

“…However, the relationship between these parameters and the time to fatigue and level of fatigue was not identified. In addition, people with PD commonly report more fatigue symptoms compared to neurologically healthy individuals [43]. Besides, time to fatigue is highly related to aging [1,6], which is difficult to control during the experiment.…”

Section: Discussionmentioning

confidence: 99%

Muscle Fatigue Does Not Change the Effects on Lower Limbs Strength Caused by Aging and Parkinson’s Disease

Pereira¹,

Barbieri²,

Zagatto³

et al. 2018

Aging and disease

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The aim of this study was to determine the impact of aging and Parkinson’s disease (PD) on lower limb muscle strength before and after muscle fatigue. One hundred thirty-five individuals were distributed over seven groups according to their age (20, 30, 40, 50, 60, 70 years old) and disease. Participants performed maximum voluntary isometric contractions (MVIC) in a leg press device followed by the muscle fatigue protocol (repeated sit-to-stand task). Immediately after muscle fatigue (less than 2 min), the MVIC were repeated. The peak force, peak rate of force development (first 50, 100, 200 ms), and root mean square and peak values of the vastus lateralis and vastus medialis muscle activity during MVIC were calculated before and after muscle fatigue. We found more pronounced reductions in lower limb muscle strength parameters (lower limb force, RFD-100 and RFD-200 - p<0.05) in individuals over 50 years of age and with PD. In addition, there was an inverse relation between aging and lower limb muscle strength parameters. The main findings were the lack of changes in peak force, RFDs and muscle activity of the vastus lateralis and vastus medialis after muscle fatigue according to aging and PD, and similar lower limb muscle strength parameters (before and after muscle fatigue) and effect of muscle fatigue in PD compared to the aged groups (60 and 70 years old groups).

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“…18 Another aspect that can impair the postural control adaptability in pwPD is the individual’s intensified perception of fatigue. 19,20 Thus, it is probable that pwPD would perform prolonged standing with minimal effort and reduced postural adjustments, avoiding any increase in musculoskeletal discomfort, as in older people. 21 Therefore, studying upright prolonged standing may clarify the postural control adaptability in pwPD.…”

Section: Introductionmentioning

confidence: 99%

Prolonged Standing Task Affects Adaptability of Postural Control in People With Parkinson’s Disease

Moretto

Santinelli

Penedo

et al. 2020

Neurorehabil Neural Repair

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Background Studies on short-term upright quiet standing tasks have presented contradictory findings about postural control in people with Parkinson’s disease (pwPD). Prolonged trial durations might better depict body sway and discriminate pwPD and controls. Objective The aim of this study was to investigate postural control in pwPD during a prolonged standing task. Methods A total of 26 pwPD and 25 neurologically healthy individuals performed 3 quiet standing trials (60 s) before completing a constrained prolonged standing task for 15 minutes. Motion capture was used to record body sway (Vicon, 100 Hz). To investigate the body sway behavior during the 15 minutes of standing, the analysis was divided into three 5-minute-long phases: early, middle, and late. The following body sway parameters were calculated for the anterior-posterior (AP) and medial-lateral (ML) directions: velocity, root-mean-square, and detrended fluctuations analysis (DFA). The body sway area was also calculated. Two-way ANOVAs (group and phases) and 1-way ANOVA (group) were used to compare these parameters for the prolonged standing and quiet standing, respectively. Results pwPD presented smaller sway area ( P < .001), less complexity (DFA; AP: P < .009; ML: P < .01), and faster velocity (AP: P < .002; ML: P < .001) of body sway compared with the control group during the prolonged standing task. Although the groups swayed similarly (no difference for sway area) during quiet standing, they presented differences in sway area during the prolonged standing task ( P < .001). Conclusions Prolonged standing task reduced adaptability of the postural control system in pwPD. In addition, the prolonged standing task may better analyze the adaptability of the postural control system in pwPD.

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Effects of Physical Activity Levels on Fatigue Perception in Patients with Parkinson’s Disease and Neurologically Healthy Individuals

Cited by 6 publications

References 29 publications

Effects of leg muscle fatigue on gait in patients with Parkinson's disease and controls with high and low levels of daily physical activity

Effects of leg muscle fatigue on gait in patients with Parkinson's disease and controls with high and low levels of daily physical activity

Muscle Fatigue Does Not Change the Effects on Lower Limbs Strength Caused by Aging and Parkinson’s Disease

Prolonged Standing Task Affects Adaptability of Postural Control in People With Parkinson’s Disease

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