Effects of Physical Exercise on Quality of Life, Exercise Capacity and Pulmonary Function in Children With Asthma

Başaran, Sibel; Güler-Uysal, Füsun; Ergen, Nilay; Seydaoğlu, Gülşah; Bingol-Karakoç, Gulbin; Altıntaş, Derya Ufuk

doi:10.1080/16501970500476142

Cited by 132 publications

(171 citation statements)

References 29 publications

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“…Failure to achieve a significant difference between groups could be due to the inclusion of subjects that are already wellcontrolled, leaving little room for improvement, and to a type II error due to small sample size. This is in contrast with the trial of BASARAN et al [34], in which a significant improvement occurred in the exercise group compared to control group. However, in that study, a significant baseline difference in symptom scores was observed between groups.…”

Section: Discussioncontrasting

confidence: 55%

Physical training does not increase allergic inflammation in asthmatic children

Moreira

Delgado²,

Haahtela³

et al. 2008

Eur Respir J

109

138

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The effects of a 3-month physical training programme on airway inflammation and clinical outcomes were studied in school-aged children with asthma.Subjects with persistent allergic asthma (aged 12.7¡3.4 yrs; n534) were randomly allocated into training and control groups. Exercise consisted of twice-weekly 50-min sessions for 12 weeks. Inflammation was assessed by levels of exhaled nitric oxide, blood eosinophils, eosinophil cationic protein, C-reactive protein, and total and mite-specific immunoglobulin (Ig)E. Lung volumes and bronchial responsiveness to methacholine were determined. The Paediatric Asthma Quality of Life Questionnaire and Paediatric Asthma Caregiver's Quality of Life Questionnaire were used to evaluate activity restrictions, symptoms and emotional stress. The efficacy of the training was assessed by accelerometry.Following the programme, the exercise group spent twice as much time as the controls undertaking moderate-to-vigorous activities. No differences in changes were seen between groups for asthma outcomes. However, total IgE decreased more in the exercise group, as did mite-specific IgE.Training did not increase inflammation in children with persistent asthma, and may have decreased both total and allergen-specific immunoglobulin E levels. It is concluded that there is no reason to discourage asthmatic children with controlled disease to exercise.

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Section: Discussioncontrasting

confidence: 55%

Physical training does not increase allergic inflammation in asthmatic children

Moreira

Delgado²,

Haahtela³

et al. 2008

Eur Respir J

109

138

View full text Add to dashboard Cite

show abstract

“…Because asthma is the most prevalent chronic disease in children and adolescents, because most asthma patients have mild intermittent or mild persistent disease, (1) and because regular physical activity has been proven to have beneficial effects, (7)(8)(9) it is essential to determine whether asthma has negative effects on exercise capacity between attacks, the approach to physical training being based on the answer to this question. Therefore, the objective of the present study was to assess children and adolescents with mild intermittent or mild persistent asthma, in terms of their aerobic capacity between attacks.…”

Section: Introductionmentioning

confidence: 99%

Capacidade aeróbica em crianças e adolescentes com asma intermitente e persistente leve no período intercrises

et al. 2012

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Objective: To assess children and adolescents diagnosed with mild intermittent or mild persistent asthma, in terms of their aerobic capacity between attacks. Methods: We included 33 children and adolescents recently diagnosed with asthma (mild intermittent or mild persistent) and 36 healthy children and adolescents. Those with asthma were evaluated between attacks. All participants underwent clinical evaluation; assessment of baseline physical activity level; pre-and post-bronchodilator spirometry; and a maximal exercise test, including determination of maximal voluntary ventilation, maximal oxygen uptake, respiratory quotient, maximal minute ventilation, ventilatory equivalent, ventilatory reserve, maximal HR, SpO 2 , and serum lactate. Results: No significant differences were found among the groups (intermittent asthma, persistent asthma, and control) regarding anthropometric or spirometric variables. There were no significant differences among the groups regarding the variables studied during the maximal exercise test. Conclusions: A diagnosis of mild intermittent/ persistent asthma has no effect on the aerobic capacity of children and adolescents between asthma attacks.Keywords: Asthma; Exercise; Respiratory function tests. ResumoObjetivo: Aferir a capacidade aeróbica de crianças e adolescentes com diagnóstico de asma brônquica intermitente leve ou persistente leve no período intercrises. Métodos: Foram estudadas 33 crianças e adolescentes com diagnóstico clínico recente de asma leve intermitente e asma leve persistente, no período intercrises, e 36 crianças e adolescentes saudáveis. Foram realizadas avaliação clínica, avaliação do nível basal do nível de atividade física, espirometria antes e após o uso de broncodilatador e determinação de ventilação voluntária máxima, consumo máximo de oxigênio, quociente respiratório, ventilação minuto máxima, equivalente ventilatório, reserva ventilatória, FC máxima, SpO 2 e lactato. Resultados: Não foram encontradas diferenças significativas entre os grupos asma intermitente, asma persistente e controle em relação às variáveis antropométricas e espirométricas. Não houve diferenças significativas em relação às variáveis analisadas durante o teste de esforço máximo entre os grupos. Conclusões: O diagnóstico de asma intermitente ou persistente leve não influenciou a capacidade aeróbica em crianças e adolescentes no período intercrises.

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“…18 Although the level of evidence is not high for several of the non-pharmacologic therapies, most have little or no adverse effects. 26,27 Therefore, non-pharmacologic treatment for EIB is an area with many questions for continued research. 18,19 In fact, to our knowledge, no study has evaluated the obesityrelated inflammatory biomarkers and their influence on EIB in obese adolescents.…”

Section: Introductionmentioning

confidence: 99%

“…Despite many studies being conducted to date, there is no single agent that has been consistently shown to prevent EIB; moreover, the majority of the studies were with asthmatic patients. [25][26][27] The goal of therapy is to allow patients with EIB to participate in vigorous activity without symptoms and difficulty. 18 Although the level of evidence is not high for several of the non-pharmacologic therapies, most have little or no adverse effects.…”

Section: Introductionmentioning

confidence: 99%

The Role of Pro-inflammatory and Anti-inflammatory Adipokines on Exercise-Induced Bronchospasm in Obese Adolescents Undergoing Treatment

Silva¹,

Mello²,

Cheik

et al. 2012

Respir Care

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BACKGROUND: Recent studies have demonstrated a greater prevalence in exercise-induced bronchospasm (EIB) in obese adolescents. However, the role of pro-/anti-inflammatory adipokines and the repercussions of obesity treatment on EIB need to be explored further. Therefore, the objective of this study was to evaluate the role of pro-/anti-inflammatory adipokines on EIB in obese adolescents evaluated after long-term interdisciplinary therapy. METHODS: Thirty-five post-pubertal obese adolescents, including 20 non-EIB (body mass index [BMI] 36 ؎ 5 kg/m 2 ) and 15 EIB (BMI 36 ؎ 5 kg/m 2 ), were enrolled in this study. Body composition was measured by plethysmography, using the BOD POD body composition system, and visceral fat was analyzed by ultrasound. Serum levels of adiponectin and leptin were analyzed. EIB and lung function were evaluated according to the American Thoracic Society criteria. Patients were recruited to a 1-year interdisciplinary intervention of weight loss, consisting of medical, nutritional, exercise, and psychological components. RESULTS: Anthropometrics and lung function variables improved significantly after the therapy in both groups. Furthermore we observed a reduction in EIB occurrence in obese adolescents after treatment. There was an increase in adiponectin levels and a reduction in leptin levels after the therapy. In addition, a low FEV 1 value was a risk factor associated with EIB occurrence at baseline, and was correlated after treatment with changes in anthropometric and maximal O 2 consumption values as well as the adipokines profile. CONCLUSIONS: In the present study it was demonstrated that 1 year of interdisciplinary therapy decreased EIB frequency in obese adolescents, paralleled by an increase in lung function and improvement in pro-/anti-inflammatory adipokines.

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Effects of Physical Exercise on Quality of Life, Exercise Capacity and Pulmonary Function in Children With Asthma

Abstract: Eight weeks of regular submaximal exercise has beneficial effects on quality of life and exercise capacity in children with asthma. Submaximal basketball training is an effective alternative exercise program for asthmatic children.

Cited by 132 publications

References 29 publications

Physical training does not increase allergic inflammation in asthmatic children

Physical training does not increase allergic inflammation in asthmatic children

Capacidade aeróbica em crianças e adolescentes com asma intermitente e persistente leve no período intercrises

The Role of Pro-inflammatory and Anti-inflammatory Adipokines on Exercise-Induced Bronchospasm in Obese Adolescents Undergoing Treatment

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