2012
DOI: 10.1016/j.jep.2012.03.016
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Effects of Plantago major L. leaf extracts on oral epithelial cells in a scratch assay

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Cited by 75 publications
(68 citation statements)
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“…Both ethanol and water extracts of fresh and dried leaves had stimulating effects which makes P. major an interesting source of different bioactive substances with wound healing potential. Polyphenol-rich ethanol-based extracts had stronger effects than water extracts (7). Aucubin, one of chemical compounds of P. major, exhibited an oral wound healing effect on mice.…”
Section: Introductionmentioning
confidence: 92%
“…Both ethanol and water extracts of fresh and dried leaves had stimulating effects which makes P. major an interesting source of different bioactive substances with wound healing potential. Polyphenol-rich ethanol-based extracts had stronger effects than water extracts (7). Aucubin, one of chemical compounds of P. major, exhibited an oral wound healing effect on mice.…”
Section: Introductionmentioning
confidence: 92%
“…major [32,56,57] exhibit anti-inflammatory property, antioxidant and antibacterial, besides promoting the proliferation and migration of epithelial cells in vitro, but inhibitory at high concentrations [56] or not [55] , demanding care in the optimization of dosages. P. major contributes to accelerate the healing of chronic purulent wounds and its antibiotic action reduces the microflora present in trophic ulcers mainly with the presence of Staphylococcus aureus, resistant to most antibiotics.…”
Section: World Journal Of Pharmacy and Pharmaceutical Sciencesmentioning
confidence: 99%
“…44 It is a relatively simple and straightforward approach for analyzing cell migration in vitro. 45 In the present study, an artificial scratch with parallel borders was mechanically created as shown in Figure 7.…”
Section: Cell Migrationmentioning
confidence: 99%