“…major [32,56,57] exhibit anti-inflammatory property, antioxidant and antibacterial, besides promoting the proliferation and migration of epithelial cells in vitro, but inhibitory at high concentrations [56] or not [55] , demanding care in the optimization of dosages. P. major contributes to accelerate the healing of chronic purulent wounds and its antibiotic action reduces the microflora present in trophic ulcers mainly with the presence of Staphylococcus aureus, resistant to most antibiotics.…”