Effects of Plants Containing Secondary Metabolites on Ruminal Methanogenesis of Sheep in vitro

Rira, Moufida; Chentli, Amira; Boufenera, Souhil; Bousseboua, H.

doi:10.1016/j.egypro.2015.07.513

Cited by 34 publications

(23 citation statements)

References 32 publications

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“…The major outcome of this study is the evidence of the ability of PSM that are commonly present in livestock diet to modify the effect of (Francis et al, 2002;Besle et al, 2010;Reynaud et al, 2010). Besides, due to numerous pharmacological activities, plants rich in those PSM are often used as animal feed additives, especially to improve rumen fermentation parameters and inhibit methane production and release (Patra & Saxena, 2010;Patra & Yu, 2013;Rira, Chentli, Boufenera, & Bousseboua, 2015). Consequently, it can be assumed that PSM, including flavonoids and saponins, are constantly delivered to cattle through the forage and/or phytogenic feed additives.…”

Section: Discussionmentioning

confidence: 99%

Interactions between erythromycin, flunixin meglumine, levamisole and plant secondary metabolites towards bovine gastrointestinal motility—in vitro study

Mendel

Chłopecka

Dziekan

et al. 2017

Vet Pharm & Therapeutics

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Continued ingestion of plant secondary metabolites by ruminants can provoke pharmacological interactions with pharmaceutical agents used in animals. As some drugs and phytocompounds affect smooth muscle activity, the aim of this study was to verify the possible interaction between selected pharmaceutical agents and plant secondary metabolites towards bovine gastrointestinal motility. The interactions between phytocompounds-apigenin, quercetin, hederagenin, medicagenic acid-and medicines-erythromycin, flunixin meglumine and levamisole-were evaluated on bovine isolated abomasal and duodenal specimens obtained from routinely slaughtered cows. The obtained results confirmed the contractile effect of all three drugs used solely. Hederagenin and medicagenic acid (0.001 μM) enhanced the contractile effect of levamisole. Hederagenin additionally increased the impact of erythromycin. Both saponins (100 μM) showed synergistic effects with all tested pharmaceuticals. Apigenin and quercetin (0.001 μM) intensified the contractile response induced by erythromycin and levamisole. Moreover, both flavonoids (100 μM) showed an antagonistic interaction with all tested drugs which in that situation were devoid of the prokinetic effect. To conclude, plant metabolic metabolites such as saponins and flavonoids are potent modifiers of the effect of drugs towards gut motility. The synergy observed between phytocompounds and selected medicines can be beneficial in the treatment of cows with hypomotility disorders.

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Section: Discussionmentioning

confidence: 99%

Interactions between erythromycin, flunixin meglumine, levamisole and plant secondary metabolites towards bovine gastrointestinal motility—in vitro study

Mendel

Chłopecka

Dziekan

et al. 2017

Vet Pharm & Therapeutics

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“…The pH value is another factor that has an impact on YSE function on the reduction of methane production in rumen. In general, reduction of methane production entails an alteration in total VFA concentration 64 which relates strongly with the acetate/propionate ratio, and this ratio is dependent partly on pH 49 . Cardozo et al 68 observed that YSE increased the proportion of propionate at pH 5.5, but not at pH 7.0 in in vitro rumen environment.…”

Section: Gas Mitigation Mechanismsmentioning

confidence: 99%

“…For methane production, a recent study revealed that methane production was not affected (P>0.05) by YSE-contained diets, even at highest levels (6 g/d saponins) 48 . Nonetheless, in a latest research, YSE reduced methane significantly (P<0.05) in a dose dependent manner, in both substrates (dates byproducts and the vetch-oat) used in the trials 49 . When saponin levels were over 8 mg/mL, the decreasing percentages of methane can be as high as 60% 49 .…”

mentioning

confidence: 99%

“…Nonetheless, in a latest research, YSE reduced methane significantly (P<0.05) in a dose dependent manner, in both substrates (dates byproducts and the vetch-oat) used in the trials 49 . When saponin levels were over 8 mg/mL, the decreasing percentages of methane can be as high as 60% 49 . Decreased methane production (11%) in wether sheep by YSE (14 mL) in two 23 h runs (day 16 to day 17 of the 18 days period) was noted as well 34 .…”

mentioning

confidence: 99%

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Effects of Yucca schidigera on gas mitigation in livestock production: A review

Sun

Xiao

Shi

et al. 2017

Braz. arch. biol. technol.

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“…reported that effects of Leucaena leucaephala with Santa Ines sheep were on reduction of CH4 emissions. Recently, Rira et al (2015) found that lower CH4 production were induced with the supplementation of Acacia cyanophylla, a tanniferous plant showing high CT content (631 g/kg DM). Tan et al (2011) found that low levels of CT extracted from LL could manipulate rumen fermentation in CH4 production in terms of diverting H2 away from CH4 formation by decreasing methanogen and protozoa populations.…”

Section: Performed In Vivo Experiments By Supplementingmentioning

confidence: 99%

Mitigating the greenhouse gas balance of ruminant production by identifying plants with high tannin concentration and quantifying the methane emission in vivo

Dhanasekaran¹

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Dados Internacionais de Catalogação na Publicação (CIP) Seção Técnica de Biblioteca -CENA/USP Dhanasekaran Dinesh KumarMitigating the greenhouse gas balance of ruminant production by identifying plants with high tannin concentration and quantifying the methane emission in vivo.Mitigando o equilíbrio de gases do efeito estufa na produção de ruminantes pela identificação de plantas com concentração elevada de tanino e quantificação das emissões de metano in vivo / Dinesh Kumar Dhanasekaran; If you want to shine like a sun, first burns like a sun. Research is never the effort of a single individual and it is a team work and many have put their effort in several ways to bring this thesis to completion. and degraded neutral detergent fiber (DNDF), especially LL, which had most influence on these parameters compared to other tannin containing plants. LL had positive response on antimethanogenic effects; its nutrient degradability was higher than that of other tannin containing plants. The second study (Expt. 2) was set to evaluate the effect of different organic extracts from the whole plant methanolic extract (MHE) of LL on in vitro gas production and to characterize the chemical constituents by using gas chromatography coupled with mass spectroscopy (GC-MS). Major abundant compounds present at the relative percentages of MHE were found to be stigmasterol trimethyl ester (TMS), neophytadiene, palmitic acid TMS, α-Linolenic acid TMS and 2, 3, 5, 6-tetra methyl anisylbenzene. The effects of additions of different extracts in terms of nutrient degradability (TDOM and DNDF) were increased by all extracts. This study explained that the methanolic hexane extract and methanolic chloroform extract was effective against methanogenic activity. The objective of the third study (Expt. 3) was to study the effect of LL plant leaves on rumen fermentation, apparent nutrient digestibility, nitrogen balance and methane production in Santa Ines sheep. The animals were divided in three groups in which they were fed with (i) 88% Tifton 85-hay (Cynodon spp.) and 12% soyabean meal (Control group, n=4); (ii) 28% Tifton 85-hay (Cynodon spp.) and 72% LL plus 20 ml solution containing 10g/day/animal of PEG (With PEG group -WPEG, n=6); (iii) 28% Tifton 85-hay (Cynodon spp.) and 72% LL plus 20 ml of distilled water (without PEG group-WOPEG, n=6). Nutrient intake (dry matter, organic matter, acid detergent fiber, lignin and crude protein) were higher in WPEG and WOPEG compared to the control group, except neutral detergent fiber intake. Apparent digestibilities and nitrogen metabolism had non-significant effects between the treatments. However, CH4 emissions were significantly lower in WPEG and WOPEG than the control. Furthermore, expressions of microbial populations of methanogens in WPEG had lower tendency than that of WOPEG and control. The most salient findings of this study were that, 72% LL plant leaves using in small ruminants diets increased animal productivity, we can get more benefits in terms of replacing the source of protein in the...

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Effects of Plants Containing Secondary Metabolites on Ruminal Methanogenesis of Sheep in vitro

Cited by 34 publications

References 32 publications

Interactions between erythromycin, flunixin meglumine, levamisole and plant secondary metabolites towards bovine gastrointestinal motility—in vitro study

Interactions between erythromycin, flunixin meglumine, levamisole and plant secondary metabolites towards bovine gastrointestinal motility—in vitro study

Effects of Yucca schidigera on gas mitigation in livestock production: A review

Mitigating the greenhouse gas balance of ruminant production by identifying plants with high tannin concentration and quantifying the methane emission in vivo

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