Effects of Platelet Rich Plasma Injection on Adhesive Capsulitis: An Interventional Case Series

Çalış, Havva Talay

doi:10.14744/etd.2019.16362

Cited by 3 publications

(8 citation statements)

References 8 publications

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“…They found that at 6 weeks, PRP showed statistically significant improvements over ultrasonic therapy for pain and QuickDASH, and at 12 weeks a statistically significant improvement was observed PRP was given at baseline and at 2 weeks, and patients were followed for 12 weeks. Patients had significant improvements in the VAS score, Shoulder Pain and Disability Index scores and ROM (66).…”

Section: Prp In Adhesive Capsulitismentioning

confidence: 95%

“…PRP was given at baseline and at 2 weeks, and patients were followed for 12 weeks. Patients had significant improvements in the VAS score, Shoulder Pain and Disability Index scores and ROM ( 66 ).…”

Section: Prp In Adhesive Capsulitismentioning

confidence: 99%

“…Based on the evidence of these studies, the use of the PRP is supported in the diagnosis of AC ( 61 , 62 , 63 , 64 , 65 , 66 ). Nevertheless, there are limitations of these studies.…”

Section: Prp In Adhesive Capsulitismentioning

confidence: 99%

“…The use of PRP occurred during different stages, with different comparison groups and different extents of efficacy. While three studies did not describe the stage of AC in patients in the study ( 61 , 63 , 66 ), the New Delhi study included patients from all stages ( 65 ), Lee et al included patients from inflammation stage only (stage I) ( 64 ) and Ünlü et al included patients in the frozen stage (stage II) ( 62 ). In three studies, PRP was compared with CS ( 63 , 64 , 65 ), of which two proved PRP to be superior to CS ( 63 , 65 ) while the other was equivocal ( 64 ).…”

Section: Prp In Adhesive Capsulitismentioning

confidence: 99%

“…In three studies, PRP was compared with CS ( 63 , 64 , 65 ), of which two proved PRP to be superior to CS ( 63 , 65 ) while the other was equivocal ( 64 ). Two other studies compared the effectiveness of PRP with no control group ( 61 , 66 ) and another with saline ( 62 ).…”

Section: Prp In Adhesive Capsulitismentioning

confidence: 99%

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The role of platelet-rich plasma in shoulder pathologies: a critical review of the literature

Rosso

Morrey²,

Grezda

et al. 2023

EFORT Open Reviews

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Platelet-rich plasma (PRP) is a revolutionary treatment that harnesses the regenerative power of the body's own platelets to promote healing and tissue regeneration. While PRP therapy has emerged as a promising option for augmenting biologic healing in the shoulder, the complexity of shoulder disorders makes it difficult to draw definitive conclusions about the efficacy of PRP across different conditions and stages of disease. Our comprehensive review of twenty-four studies highlights the current state of PRP therapy in shoulder pathologies, revealing a wide variety of number of patients, control groups and results. Despite these challenges, the regenerative potential of PRP therapy is moderate in some conditions, with numerous studies demonstrating the positive effects. In conclusion, the authors of this study recommend the use of PRP therapy for adhesive capsulitis and rotator cuff repair of medium to large tears. However, they do not recommend the use of PRP for subacromial impingement or rotator cuff tears. It is up to the clinician's discretion to decide whether PRP therapy is appropriate for individual cases. However, there is still insufficient evidence to support the inclusion of PRP therapy in treatment protocols for other shoulder disorders. Therefore, further research is needed to fully explore the potential of PRP therapy in the treatment of various shoulder conditions.

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Section: Prp In Adhesive Capsulitismentioning

confidence: 95%

Section: Prp In Adhesive Capsulitismentioning

confidence: 99%

“…Based on the evidence of these studies, the use of the PRP is supported in the diagnosis of AC ( 61 , 62 , 63 , 64 , 65 , 66 ). Nevertheless, there are limitations of these studies.…”

Section: Prp In Adhesive Capsulitismentioning

confidence: 99%

Section: Prp In Adhesive Capsulitismentioning

confidence: 99%

Section: Prp In Adhesive Capsulitismentioning

confidence: 99%

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The role of platelet-rich plasma in shoulder pathologies: a critical review of the literature

Rosso

Morrey²,

Grezda

et al. 2023

EFORT Open Reviews

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Ultrasonography-Guided Hydrodissection using Platelet-Rich Plasma or Corticosteroid in Adhesive Capsulitis of the Shoulder

Hussain

Mehak

Usmani

et al. 2022

Indian Journal of Pain

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Background: Adhesive capsulitis is a condition that presents with pain and progressive limitation of both active and passive shoulder movements. It can be primary or secondary, the latter includes causes such as rotator cuff tear, cardiovascular disease, and diabetes mellitus. The American Shoulder and Elbow Surgeons defines that adhesive capsulitis is a condition of uncertain ethology characterized by a significant restriction of both active and passive shoulder motions that occur in the absence of known intrinsic shoulder disorder. Commonly described as: Stage 1 – Freezing stage, with pain and stiffness lasting around 9 months. Stage 2 – Frozen stage, with persistent stiffness lasting 4–12 months. Stage 3 – Thawing stage, with spontaneous recovery lasting 12–42 months. Ultrasonography (USG)-guided hydrodissection is used for adhesive capsulitis of the shoulder due to its cost-effectiveness and acceptance among patients. As adhesive capsulitis is postulated as an i nflammatory and fibrotic disease, easy treatment with intra-articular corticosteroids (CSs) injection may reduce synovitis, limit the development of capsular fibrosis, and alter the natural history of disease. CS injections are effective for shorter duration, but newer agents such as platelet-rich plasma (PRP) are more effective with no serious side effects. Materials and Methods: In this study, 40 patients were taken of adhesive capsulitis of the shoulder and were divided randomly into two groups. One group received injection PRP and the other group received injection CS. The outcome was recorded. Results: There was a statistically significant reduction in numeric rating scale pain scores in both the groups over a time period of 6 weeks, but the PRP injection was observed to be better in reducing the pain scores when compared to the CS injection after the 6th week (P = 0.037). Initially, the CS injection performed better in the 1st week due to anti-inflammatory action. By the 3rd week, both the injections showed a similar effect. However, at the end of the study period (6 weeks), there was a better reduction in the Shoulder Pain and Disability Index (SPADI) pain scores (P = 0.0057) and SPADI disability scores (P = 0.029) of the group PRP. Conclusion: We concluded that USG-guided hydrodissection with PRP is more effective therapy than CS in terms of reduction of pain and improvement in shoulder function in the treatment of adhesive capsulitis of shoulder.

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Platelet-Rich Plasma for Adhesive Capsulitis: A Systematic Review

Blanchard,

Harvi,

Vasudevan

et al. 2023

Cureus

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Adhesive capsulitis (AC) is a common cause of shoulder pain seen in 3%-5% of the population. Platelet-rich plasma (PRP) is platelet-rich blood with pro-inflammatory and anti-inflammatory properties that has been proposed as a treatment option for patients with AC. The purpose of this study was to analyze outcomes of range of motion (ROM) and subjective outcomes, including the visual analog scale (VAS), disability of arm, shoulder, and hand (DASH), and shoulder pain and disability index (SPADI) scores. PubMed, Embase, and Cochrane databases were searched, and manuscripts were screened using defined preferred reporting items for systematic reviews and meta-analyses (PRISMA) criteria. Two reviewers independently screened articles for inclusion/exclusion using PICOS criteria and extracted data regarding ROM and subjective outcome scores. Nineteen total articles were included. Eleven of the 19 studies recorded ROM as a dependent variable. All articles reported improved ROM with PRP injection when compared to baseline. When recording degrees of shoulder ROM in different planes at the latest follow-up, there were a total of 67 comparative data points for PRP vs. control. Of the 67 comparisons, 62 (93%) had a larger final ROM in the PRP group. VAS scores were reported in 16 of the 19 studies, DASH scores were reported in eight of the 19 articles, and SPADI scores were reported in seven of the 19 articles. VAS, DASH, and SPADI scores were all superior in the PRP group compared to the control. Two studies reported the same final VAS score, but the PRP groups had a larger overall improvement. Of the studies that reported objective ROM outcomes, the PRP group had greater ROM at the longest follow-up compared to control in the vast majority of comparisons. For the studies that reported subjective outcomes, all patients that received PRP had a decrease in VAS pain scores and an improvement in DASH and SPADI questionnaires.

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Effects of Platelet Rich Plasma Injection on Adhesive Capsulitis: An Interventional Case Series

Cited by 3 publications

References 8 publications

The role of platelet-rich plasma in shoulder pathologies: a critical review of the literature

The role of platelet-rich plasma in shoulder pathologies: a critical review of the literature

Ultrasonography-Guided Hydrodissection using Platelet-Rich Plasma or Corticosteroid in Adhesive Capsulitis of the Shoulder

Platelet-Rich Plasma for Adhesive Capsulitis: A Systematic Review

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