Tight gas reservoirs commonly occur in clastic formations having a complex pore structure and a high water saturation, which results in a threshold pressure gradient (TPG) for gas seepage. The micropore characteristics of a tight sandstone gas reservoir (Tuha oilfield, Xinjiang, China) were studied, based on X-ray diffraction, scanning electron microscopy and high pressure mercury testing. The TPG of gas in cores of the tight gas reservoir was investigated under various water saturation conditions, paying special attention to core permeability and water saturation impact on the TPG. A mathematical TPG model applied a multiple linear regression method to evaluate the influence of core permeability and water saturation. The results show that the tight sandstone gas reservoir has a high content of clay minerals, and especially a large proportion of illite-smectite mixed layers. The pore diameter is distributed below 1 micron, comprising mesopores and micropores. With a decrease of reservoir permeability, the number of micropores increases sharply. Saturated water tight cores show an obvious non-linear seepage characteristic, and the TPG of gas increases with a decrease of core permeability or an increase of water saturation. The TPG model has a high prediction accuracy and shows that permeability has a greater impact on TPG at high water saturation, while water saturation has a greater impact on TPG at low permeability.Energies 2019, 12, 4578 2 of 13 nanometer, which strongly affects the seepage ability of gas in tight gas reservoirs [6]. In addition, it also has a characteristic of high water saturation in tight gas reservoirs, the influence of water saturation on gas seepage is very significant, and a complex relationship between water and gas will be formed [7]. The water in the pores of tight gas reservoirs forms a thin hydration film at the small pore throats, or small water droplets gather and block at the throats to produce the Jamin effect of gas seepage, which will increase the seepage resistance of gas [8][9][10]. These make gas seepage show a characteristic of non-linear seepage and a threshold pressure gradient (TPG) phenomenon in water-bearing tight gas reservoirs [11,12]. Therefore, on the basis of recognizing their micropore structures, it is necessary to study the TPG characteristic of gas in water-bearing tight gas reservoirs.The TPG of gas in water-bearing tight gas reservoirs has been accepted by most scholars, and a lot of researches have been carried out. Wojnarowski et al. [13] performed lots of liquid and gas permeability measurements on rock samples, contrasted the values of water and corrected-gas permeability, and found that water permeability was overestimated by Klinkenberg permeability, with difference in range of 11-24%. Tanikawa et al. [14] studied intrinsic permeability of sedimentary rocks using nitrogen gas and distilled water, found that gas permeability was greater than water permeability, increasing with an increase of pore pressure. Song et al. [15] investigated the influences ...