Effects of Porosity in a Seepage Model on Hemodynamics

Abstract

In this paper, we numerically investigate the effects of porosity on hemodynamics using a seepage outlet boundary condition. The results with the porosities [Formula: see text] and [Formula: see text] are compared. The comparison of the results shows that there are identical pressure, velocity and wall shear stress distributions in the artery zone; however, the velocities and wall shear stresses in the microcirculation zone with [Formula: see text] are almost as twice as those with [Formula: see text]. This work suggests that the porosity changes do not provoke variations in the artery zone, but they lead to the differences of the velocities and wall shear stresses in the microcirculation zone. The results may be the explanation of syndrome X.

Fluid–structure interaction analysis of hemodynamics in different degrees of stenoses considering microcirculation function

“…The permeability effects of porous media for outlet boundary condition have been discussed in our previous work. 29 The potential implication in clinical management is that understanding the importance of microcirculation not only provides a method for early risk detection of arterial diseases, but also affords an approach for risk stratification, medical interventions to avoid disease progression in the pathophysiological process.…”