Effects of Positive End-Expiratory Pressure on Intracranial Pressure and Cerebral Perfusion Pressure

Videtta, Walter; Villarejo, Fernando; Cohen, Myra; Domeniconi, G.; Cruz, Roberto Santa; Pinillos, O.; Ríos, Fernando; Maskin, Bernardo

doi:10.1007/978-3-7091-6738-0_25

Cited by 42 publications

(45 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In studying ventilated patients with brain injury and ICP monitors, researchers have made observations about the relationship of elevated ICP to ventilator modes. An important observation is the relationship of positive endexpiratory pressure (PEEP) to ICP [19][20][21][22][23][24][25][26][27][28]. Clinicians have observed that as PEEP increases in patients with lung injury, ICP often increases [28].…”

Section: Hypo/hypercapniamentioning

confidence: 99%

See 1 more Smart Citation

Neurologic Injury and Mechanical Ventilation

2008

View full text Add to dashboard Cite

Mechanical ventilation in neurologically injured patients presents a number of unique challenges. Patients who are intubated due to a primary neurologic injury often experience respiratory phenomena secondary to that injury, including elevation of intracranial pressure (ICP) in response to mechanical ventilation and variations in respiratory patterns. These problems often require unique ventilator strategies that are designed to minimize the impact of the ventilator on ICP and brain oxygenation. Balancing the need to maintain brain oxygenation and control of ICP can be complicated by the effects of ventilator management on ICP. We will examine the consequences of ventilator management as they relate to parameters that affect ICP and brain oxygenation in patients who have neurologic injury.

show abstract

Section: Hypo/hypercapniamentioning

confidence: 99%

“…Clinicians have observed that as PEEP increases in patients with lung injury, ICP often increases [28]. Although this observation has not been made in all patients with head injury, it has been observed that ICP can increase to dangerously high levels in response to elevated PEEP [19][20][21][22][23][24][25][26][27][28].…”

Section: Hypo/hypercapniamentioning

confidence: 99%

Neurologic Injury and Mechanical Ventilation

2008

View full text Add to dashboard Cite

show abstract

“…In patients with acute respiratory distress syndrome, but no neurological disease, who were examined by Schramm and colleagues [16] using TCD sonography, higher levels of PEEP (9.2-14.3 cm H 2 O) had no influence on cerebral blood flow, but there were signs of impaired autoregulation in 55% of patients. Videtta et al [30] found no significant increase in ICP (using a parenchymal sensor) when they elevated the PEEP from 5 to 15 cm H 2 O in 20 patients. In that study the patients suffered from severe head injury or from some type of intracranial haemorrhage.…”

Section: Auto Regulation Icp and Neurovascular Couplingmentioning

confidence: 97%

Influence of Positive End-Expiratory Pressure Ventilation on Cerebral Perfusion and Cardiac Hemodynamics

Backhaus¹,

Torka²,

Ertl³

et al. 2017

J Depress Anxiety

View full text Add to dashboard Cite

“…48 Another observa-organs are still at risk. 76 77 It may therefore be rational to maintain PEEP as low as possible as long as higher concentrations of oxygen can be avoided.…”

Section: Map Target Valuementioning

confidence: 99%

Critical Care Management Focused on Optimizing Brain Function After Cardiac Arrest

Nakashima

Hifumi

Kawakita

et al. 2017

Circ J

View full text Add to dashboard Cite

The discussion of neurocritical care management in post-cardiac arrest syndrome (PCAS) has generally focused on target values used for targeted temperature management (TTM). There has been less attention paid to target values for systemic and cerebral parameters to minimize secondary brain damage in PCAS. And the neurologic indications for TTM to produce a favorable neurologic outcome remain to be determined. Critical care management of PCAS patients is fundamental and essential for both cardiologists and general intensivists to improve neurologic outcome, because definitive therapy of PCAS includes both special management of the cause of cardiac arrest, such as coronary intervention to ischemic heart disease, and intensive management of the results of cardiac arrest, such as ventilation strategies to avoid brain ischemia. We reviewed the literature and the latest research about the following issues and propose practical care recommendations. Issues are (1) prediction of TTM candidate on admission, (2) cerebral blood flow and metabolism and target value of them, (3) seizure management using continuous electroencephalography, (4) target value of hemodynamic stabilization and its method, (5) management and analysis of respiration, (6) sedation and its monitoring, (7) shivering control and its monitoring, and (8) glucose management. We hope to establish standards of neurocritical care to optimize brain function and produce a favorable neurologic outcome.

show abstract

Effects of Positive End-Expiratory Pressure on Intracranial Pressure and Cerebral Perfusion Pressure

Cited by 42 publications

References 32 publications

Neurologic Injury and Mechanical Ventilation

Neurologic Injury and Mechanical Ventilation

Influence of Positive End-Expiratory Pressure Ventilation on Cerebral Perfusion and Cardiac Hemodynamics

Critical Care Management Focused on Optimizing Brain Function After Cardiac Arrest

Contact Info

Product

Resources

About