Effects of positive pressure on both femoral venous and arterial blood velocities and the cutaneous microcirculation of the forefoot

Fromy, Bérengère; Legrand, M.; Ábrahám, Pierre; Lefthériotis, Georges; Calès, Paul; Saumet, J. L.

doi:10.1016/s0008-6363(97)00181-8

Cited by 6 publications

(4 citation statements)

References 26 publications

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“…In the upper portion of the leg, the common femoral vein (CFV) of acute DVT patients can vary from 5.00–21.70 mm in diameter, while the popliteal vein varies from 3.80–14.40 mm (Hertzberg et al, 1997). Blood flow velocities in the CFV varies widely from 6 cm/s to 40 cm/s, as found from a study of young healthy adults (Fromy et al, 1997). In DVT patients, the blood flow downstream from the occluded or partially occluded vein where the treatment is needed would be slower.…”

Section: Discussionmentioning

confidence: 68%

Non-Invasive Embolus Trap Using Histotripsy—An Acoustic Parameter Study

Park

Maxwell

Owens

et al. 2013

Ultrasound in Medicine & Biology

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Free-flowing particles in a blood vessel were observed to be attracted, trapped, and eroded by a histotripsy bubble cloud. This phenomenon may be used to develop a Non-Invasive Embolus Trap (NET) to prevent embolization. This study investigates the effect of acoustic parameters on the trapping ability of the NET generated by a focused 1.063MHz transducer. The maximum trapping velocity, defined by the maximum mean fluid velocity at which a 3–4 mm particle trapped in a 6 mm diameter vessel phantom, increased linearly with peak negative pressure (P−) and increased as the square root of pulse length and pulse repetition frequency (PRF). At 19.9 MPa P−, 1000 Hz PRF and 10 cycle pulse length, a 3 mm clot-mimicking particle could remain trapped under a background velocity of 9.7 cm/s. Clot fragments treated by NET resulted in debris particles < 75 μm. These results will guide the appropriate selection of NET parameters.

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Section: Discussionmentioning

confidence: 68%

Non-Invasive Embolus Trap Using Histotripsy—An Acoustic Parameter Study

Park

Maxwell

Owens

et al. 2013

Ultrasound in Medicine & Biology

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“…From a theoretical point of view, there is, despite all positive effects on the venous macro-circulation, the possibility of a compression-related negative net balance of the capillary perfusion. Results from Fromy et al 26 support this hypothesis. In their own material, the tcpO 2 decreased by 5-10% over the treatment period when using regular compression stockings; whether or not this difference is of clinical relevance remains unknown, although, overall positive effects of compression seem to outweigh negative ones as shown by clinical outcome studies.…”

Section: Discussionmentioning

confidence: 87%

Clinical value of interwoven silver fibres in class II compression stockings: results from a crossover trial

et al. 2006

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Objective: The aim of the study was to show whether silver fibres interwoven into regular compression stockings will enhance the nutritive capillary perfusion in chronic venous insufficiency (CVI) patients. Methods: Double-blind, randomized crossover trial with two 10-day treatment phases and an intermediate three-day wash-out in 20 CVI patients (7 males, 13 females, median age: 65 years), comparing regular and silver fibres containing class II compression stockings. Primary endpoint: tcpO2 measurement at 44°C probe temperature in the peri-malleolar region of the reference leg. Results: In the overall study population, the 'end-of-treatment-phase' minus 'start-of-treatment-phase' tcpO2 – differences were negative for the regular hosiery (median [MAD]: -6.75 [8.5] mmHg, supine leg position; -7.25 [5.75] mmHg, dependent leg position), but positive for the silver fibre containing fabric (median [MAD]: 4.0 [7.75] and 2.5 [8.5] mmHg for the supine and the dependent leg position). The intergroup differences in the overall data were not statistically significant. Analysis of a core data-set, excluding data points above the 90% and below the 10% percentile, approached ( P = 0.052, supine) or reached statistical significance ( P = 0.023, dependent leg position). Conclusions: The study provides first evidence that using interwoven silver fibres in class II compression stockings results in clinical benefit for CVI patients.

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“…72,73 Oedema and/or venous ulcers in mixed pathology CVI or lymphoedema and/or PAOD Compression does not always reduce arterial inflow, as several experiments have demonstrated that the use of compression can even lead to an increased arterial flow in healthy individuals. [74][75][76] Because arterial occlusive disease is a frequent condition, especially in older age groups, this applies particularly to patients with venous and lymphatic diseases. In a population of 1416 patients with VLUs, 16% had concomitant arterial occlusive disease, 2% had critical ischaemia and 14% had an ABPI between 0.5 and 0.85.…”

Section: Oedema In Heart Failurementioning

confidence: 99%

Risks and contraindications of medical compression treatment – A critical reappraisal. An international consensus statement

Rabe

Partsch

Morrison³

et al. 2020

Phlebology

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Objectives Medical compression therapy is used for non-invasive treatment of venous and lymphatic diseases. Medical compression therapy-associated adverse events and contraindications have been reported, although some contraindications are theoretically based. This consensus statement provides recommendations on medical compression therapy risks and contraindications. Methods A systematic literature search of medical compression therapy publications reporting adverse events up until November 2017 was performed. A consensus panel comprising 15 international experts critically reviewed the publications and formulated the recommendations. Results Sixty-two publications reporting medical compression therapy adverse events were identified. The consensus panel issued 21 recommendations on medical compression therapy contraindications and adverse event risk mitigation, in addition to reviewing medical compression therapy use in borderline indications. The most frequently reported non-severe medical compression therapy-associated adverse events included skin irritation, discomfort and pain. Very rare but severe adverse events, including soft tissue and nerve injury, were also identified. Conclusion This consensus statement summarises published medical compression therapy-associated adverse events and contraindications, and provides guidance on medical compression therapy. Severe medical compression therapy-associated adverse events are very rarely encountered if compression is used correctly and contraindications are considered.

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Effects of positive pressure on both femoral venous and arterial blood velocities and the cutaneous microcirculation of the forefoot

Cited by 6 publications

References 26 publications

Non-Invasive Embolus Trap Using Histotripsy—An Acoustic Parameter Study

Non-Invasive Embolus Trap Using Histotripsy—An Acoustic Parameter Study

Clinical value of interwoven silver fibres in class II compression stockings: results from a crossover trial

Risks and contraindications of medical compression treatment – A critical reappraisal. An international consensus statement

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