“…Inanition Jackson (1915) and Selye (1936) made early observations on the in creased weights of rat adrenals as the result of underfeeding and starvation. Similar observations were made later by Sarason (1943) and by Mulinos, Pomerantz and Lojkin (1942). D'Angelo, Gordon and Charipper (1948) stated that the enlargement of the adrenals in guinea pigs was a characteristic response to deprivation of food.…”