Effects of Psychoactive Massage in Outpatients with Depressive Disorders: A Randomized Controlled Mixed-Methods Study

Arnold, Michaela Maria; Müller‐Oerlinghausen, B.; Hemrich, Norbert; Bönsch, Dominikus

doi:10.3390/brainsci10100676

Cited by 22 publications

(14 citation statements)

References 56 publications

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“…We are confident that massage can be clinically effective through the emotional power of touch and psychological interaction with PSD patients [42]. Many PSD patients who received Tuina with herbal ointment had a good treatment experience in China [22,43].…”

Section: Discussionmentioning

confidence: 99%

The efficacy of Tuina with herbal ointment for patients with post-stroke depression: study protocol for a randomized controlled trial

Tao

Kong

Fang

et al. 2021

Trials

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Background Post-stroke depression (PSD) is a common complication after stroke which hinders functional recovery and return to social participation of stroke patients. Efficacy of conventional drug therapies for patients with PSD is still uncertain. Therefore, many patients prefer to use complementary and alternative therapies for PSD. Tuina (traditional Chinese manual manipulation) with herbal ointment is an integration of manual therapy, and ointment is an important part of traditional Chinese medicine (TCM) therapy. Preliminary experiments have shown that the Tuina with herbal ointment can improve the mental state of patients with PSD. The purpose of this study is to observe and verify the efficacy of Tuina combined with herbal ointment for patients with post-stroke depression, and to lay a foundation for further research on its mechanism of action. Methods/design In this study, a randomized controlled trial will be conducted in parallel, including two intervention groups: Tuina with herbal ointment group and herbal ointment for control group. A total of 84 eligible participants will be randomly assigned to the groups in a 1:1 ratio. All participants will receive conventional antidepressant venlafaxine treatment (75 mg QD), on which they received two different interventions. The interventions for both groups will be carried out 5 times each week for a period of 2 weeks. The primary outcome will be the Hamilton Rating Scale for Depression (HAMD). Secondary outcomes will include transcranial magnetic stimulation (TMS), as well as 36-item Short-Form Health Survey (SF-36) and Treatment Emergent Symptom Scale (TESS). They will be assessed at the baseline, at the end of the intervention (2 weeks), and during the 1 month and 3 months of follow-up by repeated measures analysis of variance. The significance level is 5%. Adverse events will be monitored at each visit to assess safety. All outcomes will be assessed and analyzed by researchers blinded to the treatment allocation. The purpose of this study will focus on observing the efficacy of Tuina with herbal ointment for patients with post-stroke depression, and to explore further the mechanisms of its effects. Discussion This study may evaluate clinical application value and safety of Tuina with herbal ointment in PSD patients, which can provide basis for clinical research and mechanism exploration of PSD. Trial registration Chinese Clinical Trial Registry ChiCTR2000033887. Registered on 15 June 2020. Dissemination The results will be published in peer-reviewed journals and disseminated through the study’s website and conferences.

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Section: Discussionmentioning

confidence: 99%

The efficacy of Tuina with herbal ointment for patients with post-stroke depression: study protocol for a randomized controlled trial

Tao

Kong

Fang

et al. 2021

Trials

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“…Embodied cognition involves mind–body behaviors that are not always brain-centric [ 78 , 79 ], and can be described as complex psychomotor interactions [ 80 , 81 ]. For example, our largest sensory organ for interoception, nociception, and proprioception is the highly innervated fascial system [ 82 , 83 ].…”

Section: Critical Realist Framing Of Psychomotor Experiencementioning

confidence: 99%

Psychomotor Predictive Processing

Fox

2021

Entropy

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Psychomotor experience can be based on what people predict they will experience, rather than on sensory inputs. It has been argued that disconnects between human experience and sensory inputs can be addressed better through further development of predictive processing theory. In this paper, the scope of predictive processing theory is extended through three developments. First, by going beyond previous studies that have encompassed embodied cognition but have not addressed some fundamental aspects of psychomotor functioning. Second, by proposing a scientific basis for explaining predictive processing that spans objective neuroscience and subjective experience. Third, by providing an explanation of predictive processing that can be incorporated into the planning and operation of systems involving robots and other new technologies. This is necessary because such systems are becoming increasingly common and move us farther away from the hunter-gatherer lifestyles within which our psychomotor functioning evolved. For example, beliefs that workplace robots are threatening can generate anxiety, while wearing hardware, such as augmented reality headsets and exoskeletons, can impede the natural functioning of psychomotor systems. The primary contribution of the paper is the introduction of a new formulation of hierarchical predictive processing that is focused on psychomotor functioning.

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“…Alternatively, sensory interventions that promote interoceptive afferent activity (including vagal afferents) that signal safety and connection with others and that, in turn, modulate top-down regulation of the autonomic system could be considered. Recently developed sensory techniques include slow-stroke psycho-regulatory massage (Arnold et al, 2020; Baumgart et al, 2020). These interventions could potentially support the healing process on the level of the autonomic nervous system by encouraging activation of the restorative parasympathetic system and supporting the shift of the autonomic nervous system from a defensive to a restorative state.…”

Section: Neurobiological Modelsmentioning

confidence: 99%

Asylum-seeking children in shutdown: Neurobiological models

Kozlowska

Scher

Helgeland

et al. 2021

Developmental Child Welfare

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Asylum-seeking children presenting in the shutdown state have been the subject of much discussion and controversy—on both government and medical system levels—in Australia and in Sweden. In this article, we conceptualize the shutdown state as an evolutionary response to extreme threat. We adopt a neuroscience approach to present five plausible models for explaining this shutdown state, their strengths and shortcomings, and the overlaps between them. Model 1—the sustained autonomic arousal model—draws on polyvagal theory. Model 2—the innate-defence model—draws on research pertaining to animal and human innate defence responses. Model 3—the catatonia model—draws on clinical and research data with patients presenting with catatonia. Model 4—the hypometabolic model—draws on an emerging body of work pertaining to hypometabolic states in animals and humans. Model 5—the defence cascade model of dissociation—draws on clinical research pertaining to human trauma states that present as dissociation. At present, each of the models provides a plausible pathophysiological explanation—or a component of a potential pathophysiological explanation—and none of them, for the moment, has enough evidence to be either accepted or disregarded. We hope that our discussion of the models advances scientific discussion and opens up possibilities for effective treatment.

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Effects of Psychoactive Massage in Outpatients with Depressive Disorders: A Randomized Controlled Mixed-Methods Study

Cited by 22 publications

References 56 publications

The efficacy of Tuina with herbal ointment for patients with post-stroke depression: study protocol for a randomized controlled trial

The efficacy of Tuina with herbal ointment for patients with post-stroke depression: study protocol for a randomized controlled trial

Psychomotor Predictive Processing

Asylum-seeking children in shutdown: Neurobiological models

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