Effects of PUFAs on animal reproduction: male and female performances and endocrine mechanisms

Maranesi, Margherita; Castellini, Cesare; Dall’Aglio, Cecilia; Petrucci, Linda; Mattioli, Simona; Boiti, Cristiano; Zerani, Massimo

doi:10.1007/s11101-018-9559-z

Cited by 7 publications

(6 citation statements)

References 152 publications

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“…It is reported that n-3 PUFA supplementation is needed for pregnant women who do not eat fish, since their deficiency is associated with worse pregnancy outcomes such as low birth weight and preterm delivery [ 55 , 56 ]. Besides, Margherite Maranesi et al suggested that reproductive performances such as fertility and pregnancy could be enhanced by PUFA supplementation [ 57 ]. There is little information available for the influence of maternal dietary components on neonatal immune factors in humans.…”

Section: Discussionmentioning

confidence: 99%

Association of Maternal Microbiota and Diet in Cord Blood Cytokine and Immunoglobulin Profiles

Rio-Aigé

Azagra-Boronat

Massot-Cladera

et al. 2021

IJMS

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Mothers confer natural passive immunization to their infants through the transplacental pathway during the gestation period. The objective of the present study was to establish at birth the maternal and cord plasma concentration and relationship of immunoglobulins (Igs), cytokines (CKs), and adipokines. In addition, the impact of the maternal microbiota and diet was explored. The plasma profile of these components was different between mothers and babies, with the levels of many CKs, IgM, IgG2a, IgE, IgA, and leptin significantly higher in mothers than in the cord sample. Moreover, the total Igs, all IgG subtypes, IgE, and the Th1/Th2 ratio positively correlated in the mother–infant pair. Maternal dietary components such as monounsaturated fatty acids-polyunsaturated fatty acids and fiber were positively associated with some immune factors such as IgA in cord samples. The microbiota composition clustering also influenced the plasma profile of some factors (i.e., many CKs, some Ig, and adiponectin). In conclusion, we have established the concentration of these immunomodulatory factors in the maternal–neonatal pair at birth, some positive associations, and the influence of maternal diet and the microbiota composition, suggesting that the immune status during pregnancy, in terms of CKs and Igs levels, can influence the immune status of the infant at birth.

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Section: Discussionmentioning

confidence: 99%

Association of Maternal Microbiota and Diet in Cord Blood Cytokine and Immunoglobulin Profiles

Rio-Aigé

Azagra-Boronat

Massot-Cladera

et al. 2021

IJMS

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“…Regarding the female diets, it is well documented that the addition of n-3 PUFAs affects the circulating concentrations of PUFA metabolites and hormones, influencing the growth factors on the follicular fluid, as well as in the oviduct and in the uterus [99,100]. In this regard, studying the n-3 PUFA profile of female reproductive tissues, the ovary of rabbit fed fish oil or linseed dietary supplementation shows a higher proportion of n-3 PUFAs with respect to the blood and liver (see Figure 2).…”

Section: Different Effects Of N-3 Pufasmentioning

confidence: 99%

n-3 PUFA Sources (Precursor/Products): A Review of Current Knowledge on Rabbit

Rodríguez

Rebollar

Mattioli

et al. 2019

Animals

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Simple SummaryThe nutritional quality of fat for human consumption is usually evaluated in terms of the n-6/n-3 polyunsaturated fatty acid (PUFA) ratio (with optimal values ≤4). Moreover, with respect to animal production, the standard feed is unbalanced in terms of n-6/n-3 polyunsaturated fatty acids (PUFAs) with a lower proportion of the latter. Such discrepancy negatively affects the health status of animals, the productive and reproductive performances, and the general quality of their products. Hence, n-3 PUFA intake should be promoted. The increase in n-3 PUFA proportions in animal products would also be in accordance with the human dietary recommendations that often focus on the need of increasing the intake of long-chain n-3 PUFAs. In this regard, two main strategies could be implemented, namely to furnish precursor (α-linolenic acid) or long-chain derivatives (eicosapentaenoic and docosahexaenoic acids). In the present review, the effects of different n-3 PUFA sources on biological activity, physiological/reproductive endpoints, and health implications are compared focusing on the most recent results obtained in the rabbit.AbstractThis review compares the effects of different n-3 polyunsaturated fatty acid (PUFA) sources on biological activity, physiological/reproductive endpoints, and health implications with a special emphasis on a rabbit case study. Linoleic acid (LA) and α-linolenic acid (ALA) are members of two classes of PUFAs, namely the n-6 and n-3 series, which are required for normal human health. Both are considered precursors of a cascade of molecules (eicosanoids), which take part in many biological processes (inflammation, vasoconstriction/vasodilation, thromboregulation, etc.). However, their biological functions are opposite and are mainly related to the form (precursor or long-chain products) in which they were administered and to the enzyme–substrate preference. ALA is widely present in common vegetable oils and foods, marine algae, and natural herbs, whereas its long-chain PUFA derivatives are available mainly in fish and animal product origins. Recent studies have shown that the accumulation of n-3 PUFAs seems mostly to be tissue-dependent and acts in a tissue-selective manner. Furthermore, dietary n-3 PUFAs widely affect the lipid oxidation susceptibility of all tissues. In conclusion, sustainable sources of n-3 PUFAs are limited and exert a different effect about (1) the form in which they are administered, precursor or derivatives; (2) their antioxidant protections; and (3) the purpose to be achieved (health improvement, physiological and reproductive traits, metabolic pathways, etc.).

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“…Vitamin E helps in maintaining the animal’s reproductive status ( Maranesi et al ., 2018 ; Mutalip et al ., 2018 ) such as ovulation rate ( Harrison et al ., 1984 ), conception rate ( Arechiga et al ., 1994 ), and body resistance ( Lee and Han, 2018 ; Mutalip et al ., 2018 ). Lack of vitamin E causes reproductive system failure as the accumulation of free radical damages cell membranes as well as disrupts the synthesis of steroids and prostaglandins ( Hemler and Lands, 1980 ; Staats et al ., 1988 ; Lee and Han, 2018 ; Mutalip et al ., 2018 ).…”

Section: Introductionmentioning

confidence: 99%

Impact of vitamin AD3E treatment before application of controlled intra-vaginal drug releaser (CIDR) on clinical and hematologic findings, ovarian hormones and calving rates in she camels (Camelus dromedarius)

Mohamed¹,

Khalphallah²,

Ali³

et al. 2022

Open Vet J

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Background: The scope of using controlled intra-vaginal drug releasers (CIDR) in the camel industry was small relative to that of cow, sheep, and goat. Aim: The purpose of the present study was to determine the effects of intramuscular injection of AD3E (25ml/400kg; QA11CB, Merial, France) as a premedication protocol before CIDR treatment on ovarian hormones profile and calving rate in dromedary she camels (Camelus dromedarius) through measuring concentrations of progesterone (P4) and estradiol (E2) before, during and after CIDR use. Methods: The study was conducted on she-camels (Camelus dromedarius) (n=24) aged between 6-14 years. The animals were assigned into two equal groups; CIDR treated group (CIDRgr) and AD3E plus CIDR treated group (CIDR+gr). Results: Except for haemoglobin, the clinical and haematological findings showed no remarkable change either within each independent group or between CIDRgr and CIDR+gr. Serum P4 and E2 concentrations differed significantly between the first 7 days (During CIDR use) and days from 9 to 15 (After CIDR use) in dromedary camels. Serum concentrations of P4 and E2 showed significant elevation at CIDR+gr at day 0 comparing with CIDRgr. This significant increase in serum of P4 and E2 at CIDR+gr comparing to those of CIDRgr was also observed either during CIDR use (Days 3, 5 and 7) or after CIDR use (Days 9, 11, 13 and 15). During CIDR use, serum concentrations of P4 were negatively correlated with those of E2 either in CIDRgr or in CIDR+gr, however, they were positively correlated after CIDR removal either in CIDRgr or in CIDR+gr. Regarding to the calving rate, it was highest in CIDR+gr whereas CIDRgr showed the lowest one. Conclusions: It was concluded that the AD3E pretreatment protocol of she-camels before insertion of CIDR could be used successfully during the breeding season to improve fertility in she-camels whereas the serum ovarian hormones profile and calving rates were clearly changed due to pretreatment of she-camels with AD3E before CIDR insertion.

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Effects of PUFAs on animal reproduction: male and female performances and endocrine mechanisms

Cited by 7 publications

References 152 publications

Association of Maternal Microbiota and Diet in Cord Blood Cytokine and Immunoglobulin Profiles

Association of Maternal Microbiota and Diet in Cord Blood Cytokine and Immunoglobulin Profiles

n-3 PUFA Sources (Precursor/Products): A Review of Current Knowledge on Rabbit

Impact of vitamin AD3E treatment before application of controlled intra-vaginal drug releaser (CIDR) on clinical and hematologic findings, ovarian hormones and calving rates in she camels (Camelus dromedarius)

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