Effects of radiation on paraffins as polymer-model compounds—IV. Fast-neutron irradiation effects

Seguchi, Tadao; Hayakawa, Naohiro; Tamura, Naoyuki; Katsumura, Yosuke; Τabata, Yoneho

doi:10.1016/1359-0197(91)90213-l

Cited by 1 publication

(1 citation statement)

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“…Along the secondary electron track outside the knock-on proton track, free radicals are formed. Radical migration of active species in paraffin was observed through a crosslinking effect 40 . It is important to investigate a similar process of modifications of the biomolecules.…”

Section: Discussionmentioning

confidence: 99%

Effects of neutron radiation generated in deep space-like environments on food resources

Hatsuda,

Kawasaki,

Shigenaga

et al. 2023

Sci Rep

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The impact of deep space cosmic rays on food resources is as important as the risks of cosmic rays to the human body. This study demonstrates the potential for neutrons as secondary radiation in deep space spacecraft to cause meat activation and oxidative modification of proteins and lipids. We conducted a series of experiments such as the neutron irradiation experiment, the radioactivation analysis and the biochemical analysis. Neutrons with energies from 1 to 5 MeV with doses from 0.01 Gy to 4 Gy were irradiated by the RIKEN accelerated-driven neutron source (RANS). Radioactive nuclei, 24Na, 42K, and 38Cl, were detected in the neutron-irradiated meat. The modification products of the proteins by oxidative nitration, 6-nitrotryptophan (6NO2Trp), and by a lipid peroxidation, 4-hydroxy-2-nonenal (4-HNE), were detected in several proteins with neutron dose dependent. The proteome analysis showed that many oxidative modifications were detected in actin and myosin which are major proteins of myofibrils. This study is of crucial importance not only as risk factors for human space exploration, but also as fundamental effects of radiation on the components of the human body.

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Section: Discussionmentioning

confidence: 99%