We introduce designs for high-Q photonic cavities in slab architectures in hyperuniform disordered solids displaying isotropic band gaps. Despite their disordered character, hyperuniform disordered structures have the ability to tightly confine the transverse electric-polarized radiation in slab configurations that are readily fabricable. The architectures are based on carefully designed local modifications of otherwise unperturbed hyperuniform dielectric structures. We identify a wide range of confined cavity modes, which can be classified according to their approximate symmetry (monopole, dipole, quadrupole, etc.) of the confined electromagnetic wave pattern. We demonstrate that quality factors Q > 10 9 can be achieved for purely two-dimensional structures, and that for three-dimensional finite-height photonic slabs, quality factors Q > 20 000 can be maintained. A special class of disordered photonic heterostructures has recently been shown to display large isotropic band gaps comparable in width to band gaps found in photonic crystals [1][2][3]. The large band gaps found in these structures are facilitated by the hyperuniform geometrical properties of the underlying point-pattern template upon which the structures are built. The statistical isotropy of the photonic properties of these materials is highly relevant for a series of novel photonic functionalities including arbitrary angle emission or absorption and free-form waveguiding [3,4].A point pattern in real space is hyperuniform if for large R the number variance σ (R) 2 within a spherical sampling window of radius R (in d dimensions) grows more slowly than the window volume, i.e., more slowly than R d . In Fourier space, hyperuniformity means that the structure factor S(k) approaches zero as |k| → 0 [5,6]. The lack of periodicity in these hyperuniform disordered (HUD) solids demonstrates that Bragg scattering is not a prerequisite for photonic band gaps (PBGs) and that interactions between local resonances and multiple scattering are sufficient, provided that the disorder is constrained to be hyperuniform [1].The concept of optical cavities in HUD photonic materials was recently introduced in Ref. [7]. The structure analyzed was obtained by placing dielectric rods at each point of a hyperuniform point pattern. The radius of one selected rod was varied to achieve localization of the transverse magnetic (TM)-polarized electromagnetic field at that point. The study was based purely on two-dimensional (2D) structures, and vertical confinement, the primary loss pathway in real slab structures, was not discussed. The question of how to achieve index guiding and the essential vertical confinement in disordered photonic slab structures, a prerequisite of realizing cavities with high-quality factors, which can be fabricated using conventional techniques and are fully compatible with existing photonic-circuit layouts, was seen as a potential roadblock in the HUD photonic materials field.In this Rapid Communication we introduce finite-height network structures for...