The experiment was constructed with Sulphur (S) and Boron (B) with three doses of each, i.e., S0: without Sulphur (control), S20: 20kg S/ha, S30: 30kg S/ha and B0: without Boron (control), B2: 2kg B/ha, B3: 3kg B/ha to study the effect on Boro rice (cv. BRRI dhan-28). In case of Sulphur, the treatment S20 obtained the maximum plant height (97.811cm), maximum tillers hill-1 (26.184) at harvest, highest panicle length (24.98cm), maximum grains panicle-1 (167.37), maximum 1000-grain weight (27.57 g), maximum grain yield (5.46t/ha) and straw yield (5.71t/ha), maximum biological yield (11.17t/ha) and HI (48.88%). Whereas, maximum filled grains panicle-1 (147.37) and minimum unfilled grains panicle-1 (17.89) were found in S30. In case of Boron, the highest plant height (96.378 cm) was found in B3. Highest number of total tiller hill-1 (25.149), longest panicle (24.17 cm), highest number of total grains panicle-1 (165.78), filled grains panicle-1 (144.04) and minimum unfilled grains panicle-1 (21.74), maximum 1000-grain weight (25.24 g), highest grain, straw and biological yield (4.84, 5.43 and 10.27t/ha, respectively) and highest HI (47.13%) were found in B2.The treatment combination S20B2 performed the best response than other treatments. Plant height was highest (100.30 cm) in S20B3 treatment combination at harvest. However, the maximum tillers hill-1 (28.78) at harvest, highest panicle length (26.94 cm), maximum grains panicle-1 (177.57), maximum filled grains panicle-1 (150.27) and minimum unfilled grains panicle-1 (27.30), highest 1000-grain weight (29.75 g), highest grain, straw and biological yield (6.30, 5.91 and 12.21t/ha, respectively) and higher HI (51.60%) were found in S20B2 treatment combination.