Effects of Reminiscence Therapy combined with Memory Specificity Training (RT-MeST) on depressive symptoms in older adults: A Randomized Controlled Trial Protocol

Abstract

Background: Geriatric depression has become a serious public health problem, reduced autobiographical memory and increased over-general memory, as main cognitive markers of depression, are not only associated with current depressive symptoms but also associated with the onset and course of depression, which can lead to a range of harms, economic and effective psychological interventions are urgently needed. The aim of this study was to confirm the effectiveness of reminiscence therapy combined with memory specificity training in improving autobiographical memory and depressive symptoms in older adults. Methods：In this multicenter, single-blind, three-arm parallel randomized controlled study, we aim to enroll 78 older adults aged 60 years or older with a score of ≥11 on the Geriatric Depression Scale, and participants will be randomly assigned to either the reminiscence therapy group or reminiscence therapy with memory specificity training group or usual care group. Assessments will be conducted at baseline (T0) as well as immediately post-intervention (T1), 1 (T2), 3 (T3) and 6 (T4) months post-intervention. The primary outcome measure is self-reported depressive symptoms, measured using the GDS. Secondary outcome measures included measures of autobiographical memory, rumination, and social engagement. Discussion: We believe that the intervention has played a positive role in improving autobiographical memory and depressive symptoms in older adults. Poor autobiographical memory is a predictor of depression and a major cognitive marker，improving autobiographical memory is of great significance in alleviating depression symptoms in the elderly. If our program is effective, it will provide a convenient and feasible strategy for further promoting healthy aging. Trial registration:ChiCTR2200065446