2020
DOI: 10.25000/acem.622517
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Effects of repeated sevoflurane and rivastigmine on spatial learning and memory in weanling rats

Abstract: It has been reported that repeated sevoflurane exposure induces cognitive impairment. On the other hand, there is evidence that rivastigmine can attenuate or antagonize the cognitive dysfunctions caused by anesthetic agents. The aims of this study were to determine the effect of repeated sevoflurane exposure on spatial learning and memory (SLM) in weanling rats and to assess whether rivastigmine provides protection against the neurotoxic effects of sevoflurane at this early developmental stage. Methods: Thirty… Show more

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