Effects of repetitive transcranial magnetic stimulation on non-veridical decision making

Tulviste, Jaan; Goldberg, Elkhonon; Podell, Kenneth; Bachmann, Talis

doi:10.21307/ane-2017-018

Cited by 5 publications

(2 citation statements)

References 55 publications

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“…We found only two studies with female participants. Transcranial magnetic stimulation of the left and right DLPFC in females triggered a shift toward a more CI selection bias (Tulviste, Goldberg, Podell, & Bachmann, 2016). In the study by Stratta, Daneluzzo, Bustini, Prosperini, and Rossi (2000), more females than males produced CI responses.…”

Section: Introductionmentioning

confidence: 97%

Context-dependency in the Cognitive Bias Task and Resting-state Functional Connectivity of the Dorsolateral Prefrontal Cortex

Panikratova

Dobrushina²,

Tomyshev

et al. 2020

J Int Neuropsychol Soc

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Objective: Goldberg, the author of the “novelty-routinization” framework, suggested a new pair of cognitive styles for agent-centered decision-making (DM), context-dependency/independency (CD/CI), quantified by the Cognitive Bias Task (CBT) and supposedly reflecting functional brain hemispheric specialization. To date, there are only three lesion and activation neuroimaging studies on the CBT with the largest sample of 12 participants. The present study is the first to analyze whole-brain functional connectivity (FC) of the dorsolateral prefrontal cortex (DLPFC), involved in contextual agent-centered DM. Method: We compared whole-brain resting-state FC of the DLPFC between CD (n = 24) and CI (n = 22) healthy participants. Additionally, we investigated associations between CD/CI and different aspects of executive functions. Results: CD participants had stronger positive FC of the DLPFC with motor and visual regions; FC of the left DLPFC was more extensive. CI participants had stronger positive FC of the left DLPFC with right prefrontal and parietal-occipital areas and of the left and right DLPFC with ipsilateral cerebellar hemispheres. No sex differences were found. CD/CI had nonlinear associations with working memory. Conclusions: The findings suggest that CD and CI are associated with different patterns of DLPFC FC. While CD is associated with FC between DLPFC and areas presumably involved in storing representations of current situation, CI is more likely to be associated with FC between DLPFC and right-lateralized associative regions, probably involved in the inhibition of the CD response and switching from processing of incoming perceptual information to creation of original response strategies.

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Section: Introductionmentioning

confidence: 97%

Context-dependency in the Cognitive Bias Task and Resting-state Functional Connectivity of the Dorsolateral Prefrontal Cortex

Panikratova

Dobrushina²,

Tomyshev

et al. 2020

J Int Neuropsychol Soc

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“…This understandably applies also to the mechanisms implicated in risk-related behavior. TMS has previously been used to confirm the role of the DLPFC in adaptive, nonveridical decision making (Tulviste, Goldberg, Podell, & Bachmann, 2016). The neural effect of rTMS depends on the frequency of stimulation, as well as on the intensity of stimulation and the cortical state of the subject at the time of the procedure (Silvanto & Pascual-Leone, 2008).…”

Section: Introductionmentioning

confidence: 99%

Diminished Risk-Aversion After Right DLPFC Stimulation: Effects of rTMS on a Risky Ball Throwing Task

Tulviste

Bachmann

2018

J Int Neuropsychol Soc

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Objectives: Several studies on human risk taking and risk aversion have reported the involvement of the dorsolateral prefrontal cortex (DLPFC). Yet, current knowledge of the neural mechanisms of risk-related decision making is not conclusive, mainly relying on studies using non-motor tasks. Here we examine how modulation of DLPFC activity by repetitive transcranial magnetic stimulation (rTMS) affects risk-taking behavior during a motor response task. Methods: One-Hertz rTMS to the right DLPFC was applied to monitor risk-taking and risk-aversion performance during a goal-directed risky task with motor response. Healthy participants were instructed to aim for a high score by throwing a ball as close to the ceiling as possible, while avoiding touching the ceiling with the ball. Results: One-Hertz rTMS stimulation to the right DLPFC significantly increased the frequency of ceiling hits, compared to Sham-stimulation. Conclusions: Our results suggest that the right DLPFC is a valid target for manipulating risky behavior in tasks with a motor-response. Following rTMS stimulation participants' preference shifts toward immediate awards, while becoming significantly less sensitive to potential negative consequences. The results confirm that the right DLPFC is involved in impulse control in goal-directed executive tasks. (JINS, 2019, 25, 72–78)

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Non-invasive Brain Stimulation Effects on the Perceptual and Cognitive Processes Underlying Decision-making: a Mini Review

Brunyé

2020

J Cogn Enhanc

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Effects of repetitive transcranial magnetic stimulation on non-veridical decision making

Abstract: We test the emerging hypothesis that prefrontal cortical mechanisms involved in non-veridical decision making do not overlap with those of veridical decision making. Healthy female subjects performed an experimental task assessing free choice, agent-centered decision

Cited by 5 publications

References 55 publications

Context-dependency in the Cognitive Bias Task and Resting-state Functional Connectivity of the Dorsolateral Prefrontal Cortex

Context-dependency in the Cognitive Bias Task and Resting-state Functional Connectivity of the Dorsolateral Prefrontal Cortex

Diminished Risk-Aversion After Right DLPFC Stimulation: Effects of rTMS on a Risky Ball Throwing Task

Non-invasive Brain Stimulation Effects on the Perceptual and Cognitive Processes Underlying Decision-making: a Mini Review

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