2013
DOI: 10.2478/s11536-012-0124-7
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Effects of Rhodiola rosea extract on passive avoidance tests in rats

Abstract: AbstractThe purpose was to evaluate the effects of extract of Rhodiola rosea on learning and memory processes on rats. The two series of experiments were carried out — on naïve rats and on rats with scopolamine-impaired memory. The passive avoidance tests were performed — step-down and step-through. The latency of reactions in seconds was observed in both tests. Naïve rats treated with the extract in showed the prolongation of latency of reaction of both step-down and step-thro… Show more

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Cited by 3 publications
(2 citation statements)
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“…There is some connection in the AChE inhibition and memory improvement. Because the performance of a working memory task in a mice is significantly more sensitive to disruption of cholinergic mechanisms by AChE, in the hippocampus, than performance of reference memory task [31]. As the plant extract inhibit the AChE, so it possesses some ability to improve memory function of a mice.…”
Section: Discussionmentioning
confidence: 99%
“…There is some connection in the AChE inhibition and memory improvement. Because the performance of a working memory task in a mice is significantly more sensitive to disruption of cholinergic mechanisms by AChE, in the hippocampus, than performance of reference memory task [31]. As the plant extract inhibit the AChE, so it possesses some ability to improve memory function of a mice.…”
Section: Discussionmentioning
confidence: 99%
“…Rhodiola rosea L. has been used for centuries in traditional medicinal practices in Asia, Scandinavia, and Eastern Europe to stimulate nerves, enhance physical and mental performance, improve resistance to high-altitude sickness, and treat fatigue, psychological stress, and depression [12, 13]. Salidroside (Sal), an active component extracted from Rhodiola rosea L., possesses multiple pharmacological properties, including antioxidant, antiaging, and antifatigue [12].…”
Section: Introductionmentioning
confidence: 99%