Effects of rosiglitazone on contralateral iliac artery after vascular injury in hypercholesterolemic rabbits

Abstract

Background: The objective was to evaluate the effects of rosiglitazone on iliac arteries of hypercholesterolemic rabbits undergoing balloon catheter injury in the contralateral iliac arteries.

Use of rosiglitazone before and after vascular injury in hypercholesterolemic rabbits: Assessment of neointimal formation

“…This animal model was based on previous studies where rabbits develop hypercholesterolemia rapidly after excessive cholesterol feeding [ 2 , 3 , 22 , 24 ]. The metabolic effects of high cholesterol-containing diet on rabbits were extensively explained in our previous study [ 31 ]. Rosiglitazone was used at different times for each group.…”