Effects of Schisandra chinensis Baillon (Schizandraceae) on lipopolysaccharide induced lung inflammation in mice

Alpinumisoflavone attenuates lipopolysaccharide-induced acute lung injury by regulating the effects of anti-oxidation and anti-inflammation both in vitro and in vivo

“…Inammation is a highly regulated nonspecic immune reaction that is initiated by a complex process involving the activation of immune cells, such as macrophages, and the release of pro-inammatory mediators in the affected tissue. 10,11 A persistent and uncontrolled inammatory response is the major provocation in the progression of many chronic diseases in humans, including autoimmune diseases, metabolic diseases, cancers, and organ dysfunction. 12,13 Acute lung injury (ALI) is a common clinical disease that involves widespread inammation in the lung tissues, which is the rst step in the development of lung dysfunction.…”

Effect of Schisandra chinensis Extract Supplementation on Quadriceps Muscle Strength and Fatigue in Adult Women: A Randomized, Double-Blind, Placebo-Controlled Trial

“…Several studies have reported that SC extract has effectively inhibited the damage of large arterial [3,4]. It has also been implicated in increasing endurance, accuracy of movement, and physical working capacity, as well as the control of arterial blood pressure [1] and the improvement of metabolic markers [2,5].…”

Schisandrae Fructus ethanol extract ameliorates inflammatory responses and articular cartilage damage in monosodium iodoacetate-induced osteoarthritis in rats

“…(Magnoliaceae), has been used in traditional medicine for the treatment of various medicinal purposes (Panossian and Wikman, 2008[45]; Chun et al, 2014[9]). The diverse pharmacological effects of Schisandrae Fructus include antioxidant (Kang et al, 2014[23]), anti-tumor (Lv et al, 2015[37]), hepatoprotective (Wat et al, 2016[54]), anti-septic (Kook et al, 2015[30]), neuroprotective (Lee et al, 2012[33]), anti-inflammatory (Bae et al, 2012[3]; Kang et al, 2014[24]), anti-atherosclerotic (Jeong et al, 2015[20]), and anti-atrophic (Kim et al, 2015[27][28]), and anti-diabetic effects (Kwon et al, 2011[31]). Recently we reported that Schisandrae Fructus possessed potential chondroprotective effects of the collagen matrix breakdown in a pro-inflammatory cytokine interleukin (IL)-1β-induced model in vitro (Jeong et al, 2015[21]).…”