Effects of Seasonal Allergic Rhinitis on Fatigue Levels and Mood

Allergic rhinitis: An update on disease, present treatments and future prospects

“…Different animal and human studies indicate definite biochemical basis for the altered mental status during allergy. A hypothesis proposing a common neurochemistry in allergy and depression suggests that there is increased pro-inflammatory cytokines and cholinergic hypersensitivity in both allergy and depression [119]. Cytokines have an undisputed role in AR and asthma.…”

Cognitive Effects of Allergic Rhinitis and its Treatment

“…In a study of seasonal variation in the effects of AR symptoms on mood and energy, 21 adults with positive skin-prick test sensitivity to ragweed and 20 nonallergic controls were followed through two seasons, fall and winter. Although no differences emerged between the two groups during winter, during the fall season questionnaire responses of the untreated allergic group indicated increased fatigue and sadness [7].…”

Acceptance & Commitment Therapy for ME/CFS (Chronic Fatigue Syndrome) – A feasibility study

“…The association between inflammatory markers and symptoms has also received support in for example mood disorders (77)(78)(79)(80), psychosis (81), seasonal allergy (82) and in relation to subjective health without demonstrable disease (83). It follows then, that the sickness behavior processes can be initiated without an ongoing infection, through administration of bacterial endotoxin (with a structure found on the surface of bacteria with highly potent immune-stimulatory capacity) or typhoid vaccine (79,84,85), by conditioning (86) or by stress (87).…”