Effects of Sedentarism and Treadmill Training in Mechanical Properties of Muscles of Ovariectomized Rats with High-Fat Diet

Abstract

The aim of this study is to evaluate the ability of physical training in the maintenance of muscle strength in rats with HFD (high-fat diet) after OVX (ovariectomy). Eighty Wistar rats are at eight weeks of age and weight 200 g which divided into 8 groups (n = 10) and treated for 12 weeks: GA: OVX + ND (normal diet), GB: OVX + ND + training, GC: sham + ND, GD: sham + ND + training, GE: OVX + HFD, GF: OVX + HFD + training, GG: sham + HFD and GH: sham + HFD + training. HFD consists of standard ration for rats with addition of 30% lipids. In training groups, physical training five training/week was conducted on a treadmill with adaptation period of three weeks up to 18 m/s for one hour, training were performed for 12 weeks. The sedentary animals remained in individual box. To analyze the effects of training and diet, tensile strength tests of the gastrocnemius muscles were conducted: the speed of 0.1 mm/min. Analysis of variance was performed to compare groups. The mean (SD) obtained for the maximum load (N) were: