Effects of sedentary activity and physical activity on bone mineral density and fat in America: National Health and Nutrition Examination Survey, 2011–2018

Abstract

Summary We compared the relationship between sedentary activity (SA) and physical activity (PA) with bone mineral density (BMD) and body fat percentage in the United States and found a negative association between SA and BMD and a positive association with body fat percentage. a positive association between PA and BMD and a negative association with body fat percentage. Introduction SA and PA are associated with changes in skeletal parameters and body fat percentage, and we aimed to investigate and compare the relationship between SA, PA and bone mineral density (BMD) and body fat percentage in men and women. Methods We assessed the relationship between SA, PA and BMD and body fat percentage in 9249 Americans aged 20-80 years (mean age 38.26 ± 11.39 years) from NHANES 2011-2018.BMD and body fat percentage were measured by dual-energy X-ray bone densitometry (DXA). We used multiple linear regression models to examine the relationships between SA, PA and total BMD and total body fat percentage, adjusted for a large number of confounding factors. Results After adjusting for race/ethnicity, age, alcohol and smoking behavior, body mass index (BMI), total protein, blood calcium, blood uric acid, cholesterol, blood phosphorus, and blood urea nitrogen, SA was negatively associated with total BMD (β =-0.002 95% CI: -0. 003-0.001, P < 0.001) and SA was positively associated with total lipid percentage (β =0.149 95% CI: 0.111-0.186, P < 0.001). There was a positive correlation between multiple PAs and BMD and a negative correlation between multiple PAs and percent body fat. Conclusions Our results show that physical activity is a key component of maintaining bone health in both men and women and is strongly associated with lower body fat percentages. Sedentary activity has deleterious effects on skeletal homeostasis and is strongly associated with increased body fat percentage. Healthcare policymakers should advise people to be less sedentary and more physically active in the prevention of osteoporosis and obesity.

Standardizing Physical Activity Monitoring in Patients With Degenerative Lumbar Disorders

“…Interestingly, with a mean (±SD) daily step count of 5556 (±3978), patients in our study showed considerably lower real-life physical activity when compared with the standardized reference of 7511 (2805) steps per day within the MIPACT study. 2 This is important because lower activity has recently been associated with an increase in cardiovascular diseases, obesity, and overall mortality, 1-5 suggesting that the decrease in baseline activity of patients with DTD seen in our study might itself have a detrimental effect on patients' general health. Understanding the specific impact of DTD on patients' baseline physical activity in relation to normative values is therefore a crucial step to establish treatment goals that can not only indicate the success of an intervention but may also be associated with reduction in overall morbidity and mortality.…”

“…Neurosurgery 94:788-796, 2024 https://doi.org/10.1227/neu.0000000000002755 I nactivity has profound consequences on our health because it is associated with increased cardiovascular risk, obesity, and allcause mortality in the general population. [1][2][3][4][5] Patient with degenerative thoracolumbar disorders (DTDs) typically suffer from various degrees of pain and functional impairment that negatively affect real-life physical activity. 6,7 Given the associated increase in morbidity and mortality, a baseline reduction in physical activity because of DTD would thus have a significant impact on a patient's general health that may extend well beyond the known impairment in quality of life.…”

Standardizing Continuous Physical Activity Monitoring in Patients with Cervical Spondylosis

“…shown to significantly impact general health, contributing to a higher risk of cardiovascular disease, obesity, and allcause mortality. [5][6][7][8][9] Given this projected increase in morbidity and mortality, a reduction in patients' physical activity from CS may negatively impact their overall health, in addition to contributing to pain-specific poor quality of life. Second, leveraging wearables to longitudinally monitor patients' real-life activity may provide us with new opportunities to objectively and more accurately assess outcomes before and after treatment.…”

“…Investigating the relationship between CS self-reported functional disability and daily physical activity may have important clinical implications. First, inactivity has been shown to significantly impact general health, contributing to a higher risk of cardiovascular disease, obesity, and all-cause mortality 5–9 . Given this projected increase in morbidity and mortality, a reduction in patients’ physical activity from CS may negatively impact their overall health, in addition to contributing to pain-specific poor quality of life.…”