Effects of septoplasty and septal deviation on nasal mucociliary clearance

Abstract

To evaluate the effect of septal pathology and surgery on nasal mucociliary clearance. A radioisotope method was used to measure the velocity of nasal mucociliary transport. Nasal mucociliary clearance was measured before and after septal surgery using technetium-99m macroaggregated albumin. Fifteen patients (mean age: 20 +/- 8 years; 11 males, four females) were studied pre-operatively, but scintigraphy could be repeated only in 10 patients, 2 months after surgery. A group of 10 healthy volunteers were also studied. The clearance values obtained from the preoperative period (26.25 +/- 9.45 min) were significantly higher than those of the post-operative period (15.05 +/- 6.35 min). The values obtained of control group (13.30 +/- 3.15 min) were not significantly different from the post-operative values of the patient group. Septal deviation affects the mucociliary activity. It is improved by surgery. This study showed that nasal septal deviation reduced the nasal mucociliary activity, and this can easily evaluated with scintigraphy.

The Evaluation of Nasal Mucociliary Activity After Septoplasty and External Septorhinoplasty

“…Furthermore, the mucociliary activity was found to be increased on the concave side where the airflow was higher. Uslu et al [17] investigated the effect of septal pathology and surgery on nasal MCC. Nasal MCC of 15 patients with NSD and ten healthy volunteers were measured before and 2 months after septal surgery using rhinoscintigraphy.…”

The Effect of Low-Flow Desflurane Anesthesia on Mucociliary Clearance

“…[9] Patients with pathologies such as nasal septum deviation, allergic rhinitis, nasal polyposis and sinusitis were excluded from the study due to impaired nasal mucociliary clearance. [10] Special attention was paid to perform the measurements at the same time of the day because nasal mucociliary rates vary at different times of the day. [11] Despite studies showing that nasal mucociliary functions returned to normal after septoplasty or endoscopic sinus surgery, no patient with any kind of previous nasal surgery was included in the study.…”

Comparison of the Coaxial Circle Circuit with the Conventional Circle Circuit

“…Toremalm et al [32] had previously shown that administration of dry gases arrested the activity of the mucociliary transport system. Many techniques, such as stroboscopy, photon-electron techniques and phase contrast microscopy, are used to determine ciliary beat frequency [33,34] and and rhinoscintigraphy is a method used to determine the effectiveness of drug therapy for various nasal pathologies [6,35]. However, these techniques are too expensive and not suitable for routine use.…”

“…Effective mucociliary activity is the ability of respiratory mucosal surfaces to remove foreign particles, keep the mucosal surfaces moist and fresh and regularly replenish airway fluids. The mucous and ciliary system can be assessed by measuring mucociliary clearance [4][5][6]. Ciliary function is related to temperature, osmotic pressure, acidity (pH), surgery, infections, and genetic and iatrogenic factors.…”