Effects of Shiitake Culinary-Medicinal Mushroom, Lentinus edodes (Agaricomycetes), Bars on Lipid and Antioxidant Profiles in Individuals with Borderline High Cholesterol: A Double-Blind Randomized Clinical Trial

Spim, Sara Rosicler Vieira; Pistila, Ana Maria Holtz; Pickler, Thaisa B.; Silva, Marcus Tolentino; Grotto, Denise

doi:10.1615/intjmedmushrooms.2021038773

Cited by 8 publications

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our team established the dose of 100 mg/kg/day of Ab by referring to our earlier research (Laurino et al, 2019; Spim et al, 2021), in which different doses of edible and medicinal mushrooms showed safety and efficacy (Grotto et al, 2016). This dose was chosen because as it demonstrated beneficial effects without any associated toxicity.…”

Section: Methodsmentioning

confidence: 99%

Protective effect of Agaricus bisporus mushroom against maternal and fetal damage induced by lead administration during pregnancy in rats

Caetano,

Frattes,

Segato

et al. 2023

Birth Defects Research

Self Cite

View full text Add to dashboard Cite

IntroductionLead (Pb) is a toxic pollutant, which can affect different tissues of the human body. The use of natural elements, as medicinal mushroom can reduce the toxic effects of Pb.ObjectiveWe evaluated, through preclinical tests, the oral co exposures to mushroom Agaricus bisporus (Ab) by gavage and Pb in drinking water, and the capability of Ab be a protective agent for both pregnant rats and their fetuses.MethodsFemale Wistar rats were divided into four groups (n = 5/group): Group I—Control; Group II—Ab 100 mg/kg; Group III—Pb 100 mg/L; Group IV—Ab +Pb −100 mg/kg +100 mg/L. Exposure was performed until the 19th day of gestation. On the 20th day, pregnant rats were euthanized, and the outcomes evaluated were weight gain; hematological profile; biochemical markers; oxidative stress markers; reproductive capacity; and embryo fetal development.ResultsThe characterization of mushrooms reveals them to be a valuable source of nutrients. However, Pb ingestion resulted in reduced weight gain and negative impacts on hematological and biochemical parameters. Fortunately, co administration of mushrooms helped to mitigate these negative effects and promote recovery. The mushroom also showed antioxidant activity, improving parameters of oxidative stress. In addition, Ab partially recovered the damage in fetal morphology and bone parameters.ConclusionOur findings indicated that the co administration of Ab improved the toxicity caused by Pb, and the mushroom could be used as a natural alternative as a protective/chelator agent.

show abstract

Section: Methodsmentioning

confidence: 99%

Protective effect of Agaricus bisporus mushroom against maternal and fetal damage induced by lead administration during pregnancy in rats

Caetano,

Frattes,

Segato

et al. 2023

Birth Defects Research

Self Cite

View full text Add to dashboard Cite

show abstract

“…Participants in the intervention group showed a 10% reduction in triglycerides after 66 days of consuming the bars. Their redox status was improved [63].…”

Section: Effects-reducing Risks For Cardiovascular Diseases (Lipids H...mentioning

confidence: 99%

“…The antiviral effects of crude aqueous or ethanolic extracts were found in vitro, e.g., against poliovirus type 1 (PV-1), bovine herpes virus type 1 (BoHV-1) [69], herpes simplex virus-2 (HSV-2) [63], and SARS CoV-2 [70]. The mycelial preparation LEM inhibits influenza virus by interfering with virus entry into the host cells and activation of the immune response through the type I IFN pathway [71].…”

Section: Antimicrobial Effectsmentioning

confidence: 99%

Medicinal Mushrooms as Multicomponent Mixtures—Demonstrated with the Example of Lentinula edodes

Lindequist

2024

JoF

View full text Add to dashboard Cite

Medicinal mushrooms are multicomponent mixtures (MOCSs). They consist of a large number of individual compounds, each with different chemical structures, functions, and possible pharmacological activities. In contrast to the activity of an isolated pure substance, the effects of the individual substances in a mushroom or its extracts can influence each other; they can strengthen, weaken, or complement each other. This results in both advantages and disadvantages for the use of either a pure substance or a multicomponent mixture. The review describes the differences and challenges in the preparation, characterization, and application of complex mixtures compared to pure substances, both obtained from the same species. As an example, we use the medicinal and culinary mushroom Lentinula edodes, shiitake, and some of its isolated compounds, mainly lentinan and eritadenine.

show abstract

“…The Pleurotus ostreatus protein is one such protein that has been investigated for its potential in improving the rheological properties of 3D printing ink [ 6 ]. The Lentinus edodes protein (LP) is renowned for its rich and well-balanced amino acid composition, but its rheological gel properties have not been reported [ 7 , 8 ]. We anticipate that LP will not only enhance the nutritional value of potato powder, but also improve the printability of potato ink, thereby facilitating the creation of high-quality 3D-printed food.…”

Section: Introductionmentioning

confidence: 99%

Preparation and Product Characterization of Microwaveable Food Using Lentinus edodes Protein through 3D Printing

Li,

Liu

et al. 2023

Polymers

View full text Add to dashboard Cite

The Lentinus edodes protein (LP) is a high-quality protein known for its well-balanced amino acid composition. In this study, we developed three-dimensional (3D)-printed microwaveable food using a combination of LP and potato flour, and optimized the formulation to achieve a ratio of LP: potato flour: xanthan gum: water = 2:8:1:23. The 3D-printed samples exhibited better shape, weight, and size compared to the molded samples after microwave treatment, with the most favorable microwave effect observed at a 90% filling ratio. The LP content affected the viscosity and retrogradation value of the LP–potato starch mixture. Microwave duration affected the surface hardness, interior softness, and moisture content of the product. The highest overall score of 8.295 points was obtained with a microwave processing duration of 2 min. This study lays a foundation for the development of LP-based 3D-printed food.

show abstract

Effects of Shiitake Culinary-Medicinal Mushroom, Lentinus edodes (Agaricomycetes), Bars on Lipid and Antioxidant Profiles in Individuals with Borderline High Cholesterol: A Double-Blind Randomized Clinical Trial

Cited by 8 publications

References 0 publications

Protective effect of Agaricus bisporus mushroom against maternal and fetal damage induced by lead administration during pregnancy in rats

Protective effect of Agaricus bisporus mushroom against maternal and fetal damage induced by lead administration during pregnancy in rats

Medicinal Mushrooms as Multicomponent Mixtures—Demonstrated with the Example of Lentinula edodes

Preparation and Product Characterization of Microwaveable Food Using Lentinus edodes Protein through 3D Printing

Contact Info

Product

Resources

About