Effects of short-term exercise training and activity restriction on functional capacity in patients with severe chronic congestive heart failure

Meyer, Katharina; Schwaibold, Matthias; Westbrook, Samuel; Beneke, Ralph; Hajrić, Ramiz; Görnandt, L.; Lehmann, M.; Roskamm, H.

doi:10.1016/s0002-9149(96)00527-9

Cited by 125 publications

(80 citation statements)

References 23 publications

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“…Programs need to be sustainable because the benefits of exercise are lost rapidly on cessation. 6 Programs designed for older people require testing; efficacy cannot be assumed because previous programs have not delivered the expected benefits. 7,8 In a previous trial, we found that patients with low baseline 6-minute walk (6MW) distances improved more than those with higher baseline exercise capacity, suggesting that the exercise program was insufficiently intensive to benefit fitter patients.…”

Section: Clinical Perspective On P 216mentioning

confidence: 99%

Efficacy and Cost of an Exercise Program for Functionally Impaired Older Patients With Heart Failure

Witham

Fulton

Greig

et al. 2012

Circ: Heart Failure

104

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Background-Little is known about the optimum way to deliver exercise to older, functionally impaired patients with heart failure. We tested whether an exercise program tailored to the needs of these patients could improve exercise capacity and quality of life or reduce costs to the National Health Service. Methods and Results-The study design was a parallel-group, single-blind, randomized controlled trial. Patients aged Ն70 years with symptomatic heart failure and left ventricular systolic dysfunction were randomized to either 24 weeks of exercise training or usual care. Six-minute walk distance was the primary outcome; markers of physical function, quality of life, health status, and daily activity were measured at baseline and 8 and 24 weeks. Carer strain and healthcare costs were also recorded.

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Section: Clinical Perspective On P 216mentioning

confidence: 99%

Efficacy and Cost of an Exercise Program for Functionally Impaired Older Patients With Heart Failure

Witham

Fulton

Greig

et al. 2012

Circ: Heart Failure

104

View full text Add to dashboard Cite

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“…Most of the improvement occurs by week 3 but can continue up to 6 months if compliance with the training program continues. 72,73 Not only is maximal exercise performance improved but also indices of submaximal exercise as measured by the 6-minute walk or the ventilatory threshold. 59 Changes in peak V O 2 have been reported to be greater in patients with nonischemic than with ischemic cardiomyopathy.…”

Section: Exercise Capacitymentioning

confidence: 99%

Exercise and Heart Failure

Piña¹,

Apstein²,

Balady³

et al. 2003

Circulation

878

286

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“…2,3 Carefully designed ET programs have been found to reduce symptoms, increase exercise tolerance, and improve quality of life without detrimental effect, 4 -8 and it is now believed that exercise restriction may lead to deconditioning and increased morbidity. 4 Although training benefits have been attributed predominantly to adaptations in the peripheral circulation and skeletal muscle rather than to adaptations in cardiac performance, 8,9 a possible attenuation of LV remodeling has also been documented in selected patients with LV dysfunction 10 and heart failure. 11,12 However, owing to the limited number of patients enrolled in previous randomized studies-studies for the most part conducted at a single experienced center-the impact of ET on LV remodeling and contractile function in patients with CHF has not been specifically addressed.…”

mentioning

confidence: 99%

Antiremodeling Effect of Long-Term Exercise Training in Patients With Stable Chronic Heart Failure

et al. 2003

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Background-The effects of exercise training (ET) on left ventricular (LV) remodeling in chronic heart failure are not definitively established, and the safety of ET in these patients is still debated. Methods and Results-This multicenter study investigated the long-term effect of moderate ET on LV remodeling, work capacity, and quality of life (QoL) in 90 patients with stable chronic heart failure caused by LV systolic dysfunction, randomized to a 6-month ET program (T, nϭ45) or a control group (C, nϭ45). All patients underwent resting echocardiography, a cardiopulmonary exercise test, 6-minute walking test, and QoL assessment at entry and after 6 months. At entry, end-diastolic (EDV) and end-systolic (ESV) volume, ejection fraction, work capacity, peak V O 2 , and walking distance were similar in the 2 groups. After 6 months, LV volumes diminished in T (EDV, from 142Ϯ26 to 135Ϯ26 mL/m 2 , PϽ0.006; ESV, from 107Ϯ24 to 97Ϯ24 mL/m 2 , PϽ0.05) but increased in C (EDV, from 147Ϯ41 to 156Ϯ42 mL/m 2 , PϽ0.01; ESV, from 110Ϯ34 to 118Ϯ34 mL/m 2 , PϽ0.01). Ejection fraction improved in T (PϽ0.001) but was unchanged in C (PϭNS). Significant improvement in work capacity (PϽ0.001), peak V O 2 (PϽ0.006), walking distance (PϽ0.001), and QoL (PϽ0.01) was observed in T but not in C (PϭNS). T showed a trend toward fewer (Pϭ0.05) hospital readmissions for worsening dyspnea in the absence of other adverse cardiac events. Conclusions-In stable chronic heart failure, long-term moderate ET has no detrimental effect on LV volumes and function; rather, it attenuates abnormal remodeling. Furthermore, ET is safe and effective in improving exercise tolerance and QoL. (Circulation. 2003;108:554-559.)

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Effects of short-term exercise training and activity restriction on functional capacity in patients with severe chronic congestive heart failure

Cited by 125 publications

References 23 publications

Efficacy and Cost of an Exercise Program for Functionally Impaired Older Patients With Heart Failure

Efficacy and Cost of an Exercise Program for Functionally Impaired Older Patients With Heart Failure

Exercise and Heart Failure

Antiremodeling Effect of Long-Term Exercise Training in Patients With Stable Chronic Heart Failure

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