Effects of Silicone Hydrogel Contact Lenses on Ocular Surface After Sub-Bowman’s Keratomileusis

Gao, Shaohui; Wu, Jang‐Yen; Li, Lili; Wang, Yong; Zhong, Xingwu

doi:10.3109/02713683.2013.809768

Cited by 4 publications

(4 citation statements)

References 16 publications

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“…The use of BCLs in refractive surgeries such as PRK and LASEK has been proven to be effective and safe [ 4 , 5 ]. Studies have also shown that BCLs applied immediately after LASIK can reduce flap complications and patient discomfort after surgery [ 6 , 17 ]. As SMILE is a relatively new type of refractive surgery, the clinical use of BCLs for the improvement of patients' comfort is not fully understood and requires further assessment.…”

Section: Discussionmentioning

confidence: 99%

“…It has been shown that in LASIK patients, the speed of corneal epithelium healing was faster in SiH CL wearers (4.1 ± 0.3 days) when compared to hydrogel lens wearers (4.3 ± 0.8 days) [ 13 ]; whilst another study showed that eighty percent of eyes with a SiH CLs versus 63% of eyes with hydrogels had grade 1 epithelial recovery at 5 days postsurgery [ 12 ]. Gao et al [ 17 ] also found that the corneal thickness of eyes in silicone hydrogel lens were thinner than those wearing hydrogel lens at 1 day after Sub-Bowman keratomileusis (SBK) surgery. More investigations are needed to confirm if SiH BCLs may further assist, as the results of this study suggested, in preventing or alleviating corneal oedema related with surgery procedures after SMILE.…”

Section: Discussionmentioning

confidence: 99%

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Clinical Observation of Silicon Hydrogel Contact Lens Fitted Immediately after Small Incision Lenticule Extraction (SMILE)

Wang

et al. 2020

Journal of Ophthalmology

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Purpose. To examine the immediate use of bandage contact lenses (BCLs) for improving patient comfort after small incision lenticule extraction (SMILE) surgery. Methods. This is a prospective randomized controlled study in which one hundred and seventy-eight patients undergoing SMILE were randomly allocated to three groups: group A wore BCLs for 8 hours postsurgery, group B wore BCLs for 24 hours postsurgery, and group C did not wear any BCLs postsurgery. Eight subjective symptoms including photophobia, tearing, pain, foreign body sensation, burning, blurred vision, sting, and dry eyes were prospectively evaluated at 2 hours, 4 hours, 8 hours, and 24 hours, using a questionnaire with a total score of 24. The scores of symptoms and signs were compared between the three groups. Results. There was a statistically significant time effect on scoring, which implicated a decline in symptoms over time after surgery (P<0.001). There was also a significant interaction between time and the treatment group (P<0.01). The total symptom score of groups A and B (5.85 ± 3.97 and 5.99 ± 4.67, respectively) was significantly lower than that of group C at 2 hours postsurgery (7.35 ± 4.86, P<0.05), especially in tearing and pain (P<0.05). The level of corneal oedema at 24 hours postsurgery was also statistically significantly different between the three groups (P<0.001), and the post hoc test showed that groups A and B were lower than group C (P<0.01). Conclusion. Silicon hydrogel BCLs applied immediately after SMILE surgery can relieve postsurgical symptoms of tearing and pain, improving overall patient comfort, and reduce corneal oedema. This trial is registered with ChiCTR-ONRC-13003114. Precis. The application of silicone hydrogel bandage contact lenses immediately after SMILE surgery has the potential to improve patient comfort, corneal healing, and patient satisfaction following SMILE.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Clinical Observation of Silicon Hydrogel Contact Lens Fitted Immediately after Small Incision Lenticule Extraction (SMILE)

Wang

et al. 2020

Journal of Ophthalmology

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“…Before surgery and 1 day, 1 week, 1 month, 3 months postoperatively, the following ocular surface parameters were evaluated on all participants as previously described [25]: corneal fluorescein (FL) staining, tear break-up time (TBUT), Schirmer I test (SIT), ocular surface disease index (OSDI) and central corneal sensitivity. OSDI, a 12-question survey, is one of the most widely used tools for dry eye patients to report their symptoms.…”

Section: Methodsmentioning

confidence: 99%

Early Changes in Ocular Surface and Tear Inflammatory Mediators after Small-Incision Lenticule Extraction and Femtosecond Laser-Assisted Laser In Situ Keratomileusis

Gao

Liu

et al. 2014

PLoS ONE

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PurposeTo characterize the early ocular-surface changes or tear inflammatory-mediators levels following small-incision lenticule extraction (ReLEx smile) and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK).MethodsForty-seven myopic subjects were recruited for this prospective study. Fifteen underwent ReLEx smile and thirty-two underwent FS-LASIK. Corneal fluorescein (FL) staining, tear break-up time (TBUT), Schirmer I test (SIT), ocular surface disease index (OSDI) and central corneal sensitivity were evaluated in all participants. Tears were collected and analyzed for interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), nerve growth factor (NGF) and intercellular adhesion molecule-1 (ICAM-1) levels using multiplex magnetic beads. All measurements were preformed preoperatively and 1 day, 1 week, 1 month and 3 months postoperatively.ResultsFL scores in ReLEx smile group were lower than those of FS-LASIK group 1 week postoperatively (P = 0.010). Compared to the FS-LASIK group, longer TBUT were observed in ReLEx smile group 1 month (P = 0.029) and 3 months (P = 0.045) postoperatively. No significant differences were found in tear secretion for the two groups (P>0.05). OSDI scores were higher in FS-LASIK group 1 month after surgery (P = 0.020). Higher central corneal sensitivity was observed in ReLEx smile group 1 week, 1 month and 3 months (P<0.05) postoperatively. Compared to FS-LASIK group, lower and faster recovery of IL-6 and NGF levels in tears was observed in ReLEx smile group postoperatively (P<0.05). Tears TNF-α and ICAM-1 concentrations were not significantly different between the two groups at any follow-up time (P>0.05). Moreover, IL-6 and NGF levels correlated with ocular surface changes after ReLEx smile or FS-LASIK.ConclusionsIn the early postoperative period, ReLEx smile results in milder ocular surface changes than FS-LASIK. Furthermore, the tear inflammatory mediators IL-6 and NGF may play a crucial role in the ocular surface healing process following ReLEx smile and FS-LASIK.

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“…Chapter 2: Evaluating questionnaires assessing contact lens dissatisfaction from contact lens discomfort and binocular vision disorders as a factor for DED, 81,[421][422][423][424][425][426][427][428][429][430][431][432][433] dry eye interventions involving CL use, 177,[434][435][436][437] therapeutic interventions while wearing CLs, 438 and to categorise CL wearers as those with or without CLD. 15 OSDI has also been shown to correlate with both CLDEQ-8 and CISS.…”

Section: Thesis Overviewmentioning

confidence: 99%

Associations between Binocular Vision Disorders and Contact Lens Dissatisfaction

Tilia¹,

Bakaraju

Asper

et al. 2021

Optom Vis Sci

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deepest felt thanks, are for my tolerant, forgiving, and exceptional wife, Liza. Thank you for your understanding and patience in completing this thesis, but more importantly, thank you for always being there for me for the past 30 years. Perhaps with the completion of both our theses, we can get our lives back, as they seem to have been on hold for the last 10 years. Table of contents Associations between binocular vision disorders and contact lens dissatisfaction xi Chapter 7 The Effect of Contact Lens Design on Contact Lens Dissatisfaction Associated with Binocular Vision Disorders .

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Effects of Silicone Hydrogel Contact Lenses on Ocular Surface After Sub-Bowman’s Keratomileusis

Abstract: Silicone hydrogel contact lenses played a positive role in accelerating corneal epithelial healing, enhancing tear film stability and reducing discomfort of patients in the early stage after SBK.

Cited by 4 publications

References 16 publications

Clinical Observation of Silicon Hydrogel Contact Lens Fitted Immediately after Small Incision Lenticule Extraction (SMILE)

Clinical Observation of Silicon Hydrogel Contact Lens Fitted Immediately after Small Incision Lenticule Extraction (SMILE)

Early Changes in Ocular Surface and Tear Inflammatory Mediators after Small-Incision Lenticule Extraction and Femtosecond Laser-Assisted Laser In Situ Keratomileusis

Associations between Binocular Vision Disorders and Contact Lens Dissatisfaction

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