“…The severity of the edema was defined as absent, as slight when the eyelid edema did not cover the iris edge, as moderate when it extended past the iris edge and as severe when the periorbital edema kept the eyelid closed. (4) The presence of periorbital edema, the affected eyelid, the severity and coloration of the eyelid edema were assessed every 12 hours from patient's admission at ICU to the third postoperative day (0, 12, 24, 36, 48, 60, 72 hours) and every 24 hours from the third to the seventh postoperative day (96, 120, 144, 168, 192 hours). Pupil examination was considered as performed when the nurse managed to open the patient's eyelid, with or without periorbital edema, and when it was possible to assess the pupil diameter and light reflex Pupil examination was considered as not performed when the nurse was able to open the patient's eyelid partially but was not possible to assess the pupil diameter and light reflex, or was not able to open the patient's eyelid.…”