2022
DOI: 10.1248/yakushi.22-00103
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Effects of Skin Environmental Changes by Steam Towel, Ethanol, <i>l</i>-Menthol and Carpronium on the Drug Behavior in the Minoxidil Nanoparticles-applied Mice

Abstract: We previously designed the formulation containing minoxidil (MXD) nanoparticles (MXD-NPs), and found that the MXD-NPs can mainly deliver MXD into hair bulbs via hair follicles pathway, and that the therapeutic e‹ciency for hair growth is higher in comparison with the formulation containing dissolved MXD. In this study, we investigated whether the skin environmental changes by the treatment of steam towel, ethanol, l-menthol and commercially available (CA) carpronium aŠect the drug behavior in the MXD-NPs-appli… Show more

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