Effects of social support, hope and resilience on depressive symptoms within 18 months after diagnosis of prostate cancer

Abstract

Background The prevalence of depression symptoms and related modifiable factors in prostate cancer (PCa) are not well evaluated. We aimed to assess the effects of perceived social support, hope and resilience on depressive symptoms within 18 months after diagnosis of PCa, and to evaluate the role of hope and resilience as mediators of that relationship. Method A cross-sectional study was analyzed in consecutive inpatients with PCa during the months of January 2018 and August 2019. A total of 667 patients eligible for this study completed questionnaires on demographic and clinic variables, Center for Epidemiologic Studies Depression Scale, Multidimensional Scale of Perceived Social Support, Adult Hope Scale, and Resilience Scale (14 items). All registered patients were all volunteers and anonymous. Depressive symptoms, perceived social support, hope and resilience were measured anonymously. Out of 667 patients, a total of 564 effective respondents (< 30% missing data) became our subjects. Hierarchical linear regression was used to identify the factors associated with depressive symptoms. Asymptotic and resampling strategies were used to conduct the mediating effects of hope and resilience. Results The prevalence of depressive symptoms was 65.9% in PCa patients. Hierarchical regression analyses indicated that perceived social support, hope, and resilience together accounted for 27.5% variance of depressive symptoms. Support from family, hope, and resilience significantly associated with depressive symptoms, respectively. Hope (a*b = − 0.0783, BCa95% CI: − 0.134 to − 0.0319, p < 0.05), and resilience (a*b = − 0.1315, BCa95% CI: − 0.1894 to − 0.0783, p < 0.05) significantly mediated the association between perceived social support and depressive symptoms. Conclusions The high prevalence of depressive symptoms among PCa patients should receive more attention. Perceived social support, hope and resilience could be positive resources for combating depressive symptoms, and hope and resilience mediated the association between perceived social support and depressive symptoms. Enhancing social support, particularly the support form family, and improving patients’ outlook and resilience may be potential targets for future psychosocial interventions aimed at reducing depressive symptoms.

Impact of changes in psychological resilience during treatment with intensity-modulated radiotherapy on nasopharyngeal carcinoma patients: a prospective study

“…The psychological resilience of patients with advanced lung cancer was closely related to patients' QoL (17,18). Depressive symptoms were very common in patients with prostate cancer and could affect the patient's willingness to live (19). In our study, the psychological resilience of NPC patients improved to some extent within 1 year after receiving IMRT treatment, and the average CD-RISC score increased from 55.8±7.0 to 58.4±7.8 within the 1-year period.…”

The Mediating Roles of Family Resilience and Social Support in the Relationship Between Illness Severity and Depressive Symptoms Among Primary Caregivers of Children With Epilepsy in China

“…These situations are negatively associated with their psychological health (27). As previous studies showed that high levels of social support were related to the improvement of psychological wellbeing among mothers of children with autism spectrum disorders (28) and reduction of depressive symptoms in patients with prostate cancer (29). In other words, a powerful support network can assist parents to cope with difficulties and maintain family members' mental wellbeing.…”

Hope and depression: the mediating role of social support and spiritual coping in advanced cancer patients

“…The depression of patients with advanced cancer is affected by multiple factors of body, mind, society and spirit. Previous studies have shown that depression is negatively correlated with hope and social support [ 9 ]. A study had built a mediating effect model to explore the mechanism of hope for depression [ 10 ].…”

“…Understanding the mechanism of depression can provide a reference for the intervention and treatment of patients with depression in the future. Although previous studies have explored the relationship and interaction between hope, social support, spiritual coping, and depression respectively [ 9 , 11 , 16 , 20 , 26 , 27 ], and a study has verified the mediating role of social support between hope and depression [ 18 ], but spiritual coping has not been added to the model to verify their interactions. A serial multiple mediating model was thus performed to examine the relationships among hope, social support, spiritual coping and depression.…”