Effects of sodium butyrate on the growth
performance, intestinal microflora and morphology
of weanling pigs

Lu, Jianjun; Zou, Xiaoting; Wang, Y. M.

doi:10.22358/jafs/66685/2008

Cited by 50 publications

(48 citation statements)

References 15 publications

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“…Ma et al (2012) found butyrate improving antioxidative stress ability. Improved piglet performance due to butyrate supplement was found also by Lu et al (2008) and in the experiment of Miller and Slade (2006) the positive effect of butyrate was enhanced by the addition of zinc oxide. Worse results were received by Biagi et al (2007).…”

Section: Introductionmentioning

confidence: 79%

Effect of dietary glutamine, glucose and/or sodium butyrate on piglet growth, intestinal environment, subsequent fattener performance, and meat quality

Hańczakowska

Niwińska

Grela³

et al. 2014

CZECH J ANIM SCI

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ABSTRACT:The effect of feed supplementing with glutamine, glucose and/or sodium butyrate was estimated on 156 piglets. The after-effect of supplements on fattener performance, carcass traits, and meat quality was examined. Piglets were allocated to 5 groups and fed standard feed mixture alone (control -C) or supplemented with 10 g of l-glutamine, or 10 g of glucose, or 3 g of sodium butyrate per kg of diet or all of these compounds (groups GT, GC, SB, and GT+GC+SB, respectively). Six piglets from each group were slaughtered at 63 days of age, their intestines were prepared and their parts measured. Digesta from ileum and caecum was taken for analysis. Its acidity and volatile fatty acids content were evaluated. Morphological structure of duodenal and ileal epithelium was estimated. After 84 days of age 20 animals from each group were fed the standard mixture. After 100 days of fattening 8 pigs from each group were slaughtered, pH of meat was measured, and samples of the longissimus muscle were taken for analysis. Body weight gains of piglets fed diets supplemented with SB or all supplements were higher than those of controls. All supplements given together increased total intestinal weight and length. Epithelial villi in jejunum were the highest in piglets receiving all supplements. Their height in the duodenum ranged from 296 to 347 µm and in the jejunum they were higher: 336 -424 μm. After 100 days of fattening body weight of all experimental animals was higher than that of control. There was no significant difference in carcass and meat quality. Sodium butyrate added to the diet improved piglet performance probably due to changes in intestine development and in intestinal epithelium structure. This positive effect was enhanced to some extent by the addition of glutamine or glucose.

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Section: Introductionmentioning

confidence: 79%

Effect of dietary glutamine, glucose and/or sodium butyrate on piglet growth, intestinal environment, subsequent fattener performance, and meat quality

Hańczakowska

Niwińska

Grela³

et al. 2014

CZECH J ANIM SCI

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“…Histological parameters reflect intestinal environment and are an indication of health status (Lu et al, 2008). Adding TA to the diets did not alter the colon crypt depth of rats.…”

Section: Discussionmentioning

confidence: 95%

A dose-response effects of tannic acid and protein on growth performance, caecal fermentation, colon morphology, and β-glucuronidase activity of rats

Barszcz¹,

Taciak²,

Skomiał³

2011

J. Anim. Feed Sci.

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The aim of the present work was to study the influence of tannic acid (TA) and protein level in the diet on fermentation in the caecum of rats, activity of bacterial β-glucuronidase, and colon morphology. Twelve groups of six male Wistar rats were given either a control diet free of TA or diets containing 0.25, 0.5, 1, 1.5, or 2% TA. Diets contained 10 or 18% of crude protein. Body weight and feed intake were monitored during a 3-week experimental period. Tannic acid reduced protein apparent digestibility and decreased liveweight gain. Both factors affected caecal fermentation and increased volatile fatty acid production. The higher protein level increased the concentration of branched-chain fatty acids. Tannic acid reduced the activity of β-glucuronidase and affected colonic myenteron thickness. These results indicate that TA may have advantageous effects on the gastrointestinal tract if its amount in the diet does not exceed 1.5%.

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“…Recently, sodium butyrate and Yucca schidigera have received considerable attention, but most of the studies examined their influence on growth performance and the structure, function, and microbiology of the digestive tract (10,12,14,16,19). The majority of research on Yucca schidigera has been focused on odour elimination in animal production (1).…”

Section: Discussionmentioning

confidence: 99%

“…Changes in morphology and physiology of the gastrointestinal tract had influence on metabolism and parameters of bones (4,9). Several studies have proved that the supplementation of diets with butyrate has beneficial effects on performance and digestive tract health in weaning pigs (5,10,14,32,34). However, Tonel et al (29) reported that a diet with butyrate had little effects on intestinal mucosa morphology of piglets.…”

Section: Discussionmentioning

confidence: 99%

“…In consequence, the need to utilise more efficiently acting ingredients in the diets for earlyweaned animals, which protect microflora of the gastrointestinal tract (GIT) to avoid scouring and improve performance, has encouraged the development of alternative feed additives. Especially, the ban on the use of antibiotics in EU countries in 2006 stimulated a great number of studies on the use of alternative substances, such as probiotics, acidifiers, herb extracts, enzyme cocktails, non-digestible oligosaccharides with or without prebiotic properties, and others (10,14,16,30,32). Among the currently available alternatives that might substitute antibiotics as growth promoters in diets for young pigs, organic acids are one of the most promising.…”

Section: Introductionmentioning

confidence: 99%

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Effect of sodium butyrate and Yucca schidigera extract on bone characteristics in growing pigs

Puzio¹,

Piedra

Kapica³

et al. 2016

Journal of Veterinary Research

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Introduction: The aim of this study was to investigate the influence of diet supplementation with sodium butyrate and Yucca schidigera extract (0.2% and 0.3%) on femur quality of growing pigs (n = 45). Material and Methods: At the age of 28, 35 and 56 d, five piglets from each group fed a different diet were euthanised and the femora were collected for further analyses. The bone characteristics were assessed based on weight, length, densitometric analysis of BMC and BMD, pQCT analysis (area, mineral content, volumetric density of trabecular and cortical part of metaphysis and diaphysis, respectively), ultimate strength, and geometrical parameters (cross-sectional area and second moment of inertia). Results: There were no significant differences in femur bone parameters among experimental groups on the 28 th d of life. On the 35 th d of life, piglets with 0.2% supplementation of sodium butyrate and Yucca schidigera extract had significantly lower values of weight and second moment of inertia, and significantly higher trabecular BMD and BMC compared to other experimental groups. In 56-day-old pigs, the higher values were observed in both experimental groups regarding BMC, ultimate strength, geometrical parameters, cortical BMC, diaphyseal total area, and endosteal circumference (P < 0.05). Significant differences between experimental groups were observed only in bone weight and cortical thickness. Conclusion: This study proved that simultaneous supplementation with sodium butyrate and Yucca schidigera extract positively influences bone quality in pigs in the post-weaning period. However, there were no differences in bone characteristics between the addition of 0.2% and 0.3% preparations.

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Effects of sodium butyrate on the growth performance, intestinal microflora and morphology of weanling pigs

Cited by 50 publications

References 15 publications

Effect of dietary glutamine, glucose and/or sodium butyrate on piglet growth, intestinal environment, subsequent fattener performance, and meat quality

Effect of dietary glutamine, glucose and/or sodium butyrate on piglet growth, intestinal environment, subsequent fattener performance, and meat quality

A dose-response effects of tannic acid and protein on growth performance, caecal fermentation, colon morphology, and β-glucuronidase activity of rats

Effect of sodium butyrate and Yucca schidigera extract on bone characteristics in growing pigs

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