Effects of soluble surfactants on the Langmuir monolayers compressibility: A comparative study using interfacial isotherms and fluorescence microscopy

Khattari, Z. Y.; Langer, U.; Aliaskarisohi, Saeedeh; Ray, Ayan; Fischer, Thomas M.

doi:10.1016/j.msec.2011.07.020

Cited by 20 publications

(14 citation statements)

References 45 publications

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“…Tween 60 enhanced both the lift-off area and initial surface pressure for all the systems, indicating expansion of the monolayer because of its hydrocarbon moiety 32 . In all cases, the lift-off area was found to be up-shifted when Tween 60 was used as the subphase, as compared to the lift-off area of isotherms of the amphiphiles with water as the subphase.…”

Section: Interfacial Behaviour Of the Monomolecular Lmsmentioning

confidence: 95%

Effects of Fatty Acids on the Interfacial and Solution Behavior of Mixed Lipidic Aggregates Called Solid Lipid Nanoparticles

et al. 2016

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Section: Interfacial Behaviour Of the Monomolecular Lmsmentioning

confidence: 95%

Effects of Fatty Acids on the Interfacial and Solution Behavior of Mixed Lipidic Aggregates Called Solid Lipid Nanoparticles

et al. 2016

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“…For example, a higher value of C s ¡1 indicates lower elasticity of the monomolecular film (i.e., more condensed films) and vice versa. [16] 2.2.4. Fluorescence microscopy imaging of the monolayer To observe the morphological characteristics of the monolayer at the air/water interface, a homemade mini trough was constructed.…”

Section: Compressibility Modulus Of Langmuir Monolayermentioning

confidence: 99%

Temperature effect on thin lipid film elasticity and phase separation: insights from Langmuir monolayer and fluorescence microscopy techniques

2015

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Langmuir monolayer pressure isotherms and compressibility modulus measurements of phospholipid mixtures in several Langmuir monolayer systems at the air/water interface were investigated in this study. The ultimate aim was to carry out a comparison of the elasticity modulus for monolayers with different mixtures of l,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), l,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and chicken egg yolk sphingomyelin (eSM), in the presence/absence of cholesterol (Chol). In particular, we were able to propose that the leading force beyond the phase separation into liquid expanded (LE-) and liquid condensed (LC-) phases emerges from the increasing barrier to incorporate DOPC molecules into a highly ordered LC-phase. In addition, our findings suggest that DOPC lipid molecules have a priority to incorporate in a disordered LE-phase, while DPPC and eSM prefer the ordered one. Also, Chol seems to split almost equally into both phases, indicating that Chol has no priority for either phase and there are no particular interactions between Chol and saturated lipid molecules.

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“…The lower value of C s indicates lower elasticity of the monomolecular film (i.e., more condensed films) and vice versa (32,33). The values of C s for different monolayers provide information about the elasticity and the compressibility of the corresponding cell membrane.…”

Section: Thermodynamic and Mechanical Theory Of The Binary Mixturesmentioning

confidence: 99%

“…The stability of the monolayer provides a better understanding of the molecular interaction in the binary mixture by calculating the excess of free energy G ex of mixing as a function of the viscosin molar fraction X v , for different pressure values. 7i) (33,35). 6.…”

Section: Thermodynamic Propertiesmentioning

confidence: 99%

Interaction Study of Lipopeptide Biosurfactant viscosin with DPPC and Cholesterol by Langmuir Monolayer Technique

et al. 2015

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Langmuir monolayers at the air/water interface are frequently used to establish a pseudo-physiological environment needed to study peptides and proteins properties to mimic their interaction with the cell membrane. The self-assembled monolayers formed at the air/water interface that respond to external stimuli and re-structure upon interaction with viscosin peptide in controlled environment have been studied in details. The mechanical and thermodynamic properties of the resulting monolayer are also influenced by temperature and pressure of the resulting mixture. Herein, two distinct pathways were found to contribute to equilibrium formation of DPPC and Cholesterol monolayers. Our data provided an estimate for Gibbs free energy of mixing, the elastic modulus and the classification of the final mixing behavior. Fluorescence microscopy (FM) imaging was also used to assess the morphological and structural changes within the fabricated monolayers. A molecular biological view has been established between our in vitro results and the clinical inhibition of viscosin toward the metastatic cancer and colon carcinoma cells.

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Effects of soluble surfactants on the Langmuir monolayers compressibility: A comparative study using interfacial isotherms and fluorescence microscopy

Cited by 20 publications

References 45 publications

Effects of Fatty Acids on the Interfacial and Solution Behavior of Mixed Lipidic Aggregates Called Solid Lipid Nanoparticles

Effects of Fatty Acids on the Interfacial and Solution Behavior of Mixed Lipidic Aggregates Called Solid Lipid Nanoparticles

Temperature effect on thin lipid film elasticity and phase separation: insights from Langmuir monolayer and fluorescence microscopy techniques

Interaction Study of Lipopeptide Biosurfactant viscosin with DPPC and Cholesterol by Langmuir Monolayer Technique

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