Effects of some environmental parameters on catalase activity measured in the mussel (Mytilus galloprovincialis) exposed to lindane

Khessiba, Asma; Roméo, Michèle; Aïssa, Patricia

doi:10.1016/j.envpol.2004.05.035

Cited by 117 publications

(51 citation statements)

References 22 publications

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“…However, CAT activity was induced again after 42 days of exposure, it may be due to the ROS generated by the increasing concentration of DDE and DDD, the metabolites of DDT. The results were in agreement with previous reports of the up-regulating of CAT activity in macrophytes and mussels exposed to lindane and endosulfan [36,44].…”

Section: Cat and Gst Activity Of Earthworms Exposed To Soils Spiked Wsupporting

confidence: 83%

Survival, growth, detoxifying and antioxidative responses of earthworms (Eisenia fetida) exposed to soils with industrial DDT contamination

Shi

Zhang

Huang

et al. 2016

Pesticide Biochemistry and Physiology

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The survival, growth, activity of the biotransformation system phase II enzyme glutathione-S-transferase (GST) and the oxidative defense enzyme catalase (CAT) of earthworms exposed to the contaminated soils from a former DDT plant and reference soils were investigated, and compared with the corresponding indicators in simulated soil-earthworm system, unpolluted natural soils with spiked-in DDT series, to identify the toxic effects of DDT on earthworms and their cellular defense system in complex soil system. The results indicated that DDT level in the contaminated soils was significantly higher than that in the reference soils with similar level of other pollutants and soil characters. The mortality, growth inhibition rates, GST and CST activities of earthworms exposed to the contaminated soils were significantly higher than that in reference soils. The contribution of historical DDT in contaminated soils to earthworms was confirmed by the DDT spiked tests. DDT spiked in soils at rates of higher than 200 mg·kg −1 was significantly toxic to both the survival and the growth of earthworms. DDT significantly stimulated GST and CAT activity in earthworms after 14 days. The CAT and GST activities were also stimulated by DDT exposure at rates of 100 mg·kg −1 after chronic exposure (42 days). The results provide implications for validating the extrapolation from laboratory simulated soils criteria to contaminated soils and for making site risk assessments.

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Section: Cat and Gst Activity Of Earthworms Exposed To Soils Spiked Wsupporting

confidence: 83%

Survival, growth, detoxifying and antioxidative responses of earthworms (Eisenia fetida) exposed to soils with industrial DDT contamination

Shi

Zhang

Huang

et al. 2016

Pesticide Biochemistry and Physiology

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“…By transforming the superoxide anion to H 2 O 2 , SOD, in fact, represents the first defensive enzyme that organisms use to limit the toxicity of ROS. However, the antioxidant defence pathway was not blocked because other enzymes, such as those included into the perixosomes, may generate H 2 O 2 (Khessiba et al 2005), which is the selective substrate for CAT and GPx. Overall, it can explain the significant (P \ 0.05) activation of these antioxidant enzymes, particularly GPx, which showed a significant (P \ 0.05) activation at the end of each exposure.…”

Section: Discussionmentioning

confidence: 96%

Sub-lethal effects induced by a mixture of three non-steroidal anti-inflammatory drugs (NSAIDs) on the freshwater bivalve Dreissena polymorpha

Parolini

Binelli

2011

Ecotoxicology

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Non-steroidal anti-inflammatory drugs (NSAIDs) are the sixth top-selling drugs worldwide and are commonly found in freshwater ecosystems in the high ng/l to low μg/l range. Recent studies have investigated both the acute and the chronic toxicity of single NSAIDs on different biological models, but these studies have completely neglected the fact that, in the environment, non-target organisms are exposed to mixtures of drugs that have unforeseeable toxicological behavior. This work investigated the sub-lethal effects induced by a mixture of three common NSAIDs, namely, diclofenac, ibuprofen and paracetamol, on the freshwater bivalve, the zebra mussel (Dreissena polymorpha). The mussels were exposed to three different environmental concentrations of the mixture (Low, Mid and High). A multi-biomarker approach was used to highlight cyto-genotoxic effects and the imbalance of the oxidative status of the treated specimens. The Neutral Red Retention Assay (NRRA) was used as a biomarker of cytotoxicity, whereas the activities of catalase, superoxide dismutase, glutathione peroxidase and glutathione S-transferase were measured to assess the role played by the oxidative stress enzymes. In addition, the single cell gel electrophoresis assay, the DNA Diffusion assay and the micronucleus test were used to investigate possible genotoxic effects. According to our NRRA results, each treatment was able to induce a significant cellular stress in bivalves, probably due to the raise of oxidative stress, as indicated by the alteration of enzyme activities measured in treated specimens. Moreover, the mixture induced significant enhancements of DNA fragmentation, which preluded fixed genetic damage, as highlighted by the increase of both apoptotic and micronucleated cells.

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“…Interestingly, some of these biomarkers were modulated depending on the season and, this, for the three contaminated sites. Therefore, modulations on biomarker responses could be due to (1) abiotic or biotic factors in this area such as temperature, salinity, pH, or food supply (Khessiba et al 2005;Kirchin et al 1992;Prevodnik et al 2007;Verlecar et al 2007), (2) modulations of contaminant contents through seasons (Niyogi et al 2001), and/or (3) an additive effect of temperature variations and contaminant contents in these areas. Indeed, Ringwood et al (2002) reported a correlation between lysosomal destabilization in deployed oysters Crassostrea virginica and tissue metal concentrations.…”

Section: Discussionmentioning

confidence: 98%

Seasonal variation of pollution biomarkers to assess the impact on the health status of juvenile Pacific oysters Crassostrea gigas exposed in situ

Luna‐Acosta

Bustamante

Godefroy

et al. 2010

Environ Sci Pollut Res

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Effects of some environmental parameters on catalase activity measured in the mussel (Mytilus galloprovincialis) exposed to lindane

Cited by 117 publications

References 22 publications

Survival, growth, detoxifying and antioxidative responses of earthworms (Eisenia fetida) exposed to soils with industrial DDT contamination

Survival, growth, detoxifying and antioxidative responses of earthworms (Eisenia fetida) exposed to soils with industrial DDT contamination

Sub-lethal effects induced by a mixture of three non-steroidal anti-inflammatory drugs (NSAIDs) on the freshwater bivalve Dreissena polymorpha

Seasonal variation of pollution biomarkers to assess the impact on the health status of juvenile Pacific oysters Crassostrea gigas exposed in situ

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