Effects of soybean meal hydrolysate as the nitrogen source on seed culture morphology and fumaric acid production by Rhizopus oryzae

Zhang, Kun; Chen, Yu; Yang, Shang‐Tian

doi:10.1016/j.procbio.2014.12.015

Cited by 57 publications

(46 citation statements)

References 30 publications

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“…The control of the fungal morphology must be exhaustively studied because different morphologies direct metabolism to different products [45]. These morphologies are the result of different operating conditions, including final pH, nitrogen amount, agitation and inoculum mass.…”

Section: Morphologymentioning

confidence: 99%

Fumaric Acid Production: A Biorefinery Perspective

et al. 2018

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The increasing scarcity of fossil raw materials, together with the need to develop new processes and technology based on renewable sources, and the need to dispose of an increasing amount of biomass-derived waste, have boosted the concept of biorefineries. Both 1G and 2G biorefineries are focused on the obtention of biofuels, chemicals, materials, food and feed from biomass, a renewable resource. Fumaric acid, and most compounds involved in the Kreb cycle, are considered key platform chemicals, not only for being acidulants and additives in the food industry, but also for their prospective use as monomers. This review is focused on the biotechnological processes based on fungi, mainly of the Rhizopus genus, whose main product is fumaric acid, on the process conditions, the bioreactors and modes of operation and on the purification of the acid once it is produced.

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Section: Morphologymentioning

confidence: 99%

Fumaric Acid Production: A Biorefinery Perspective

et al. 2018

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“…The beneficial effect of commercial soybean peptone on the morphology of R. oryzae ATCC 20344 and R. oryzae NRRL 1526 has been reported in other studies [10,11,14]. Zhang et al [12] showed that chemical hydrolysate derived from soybean meal can be utilised in the pre-culture medium of R. oryzae ATCC 20344 for fumaric acid production. Particularly, the utilisation of soybean meal hydrolysate led to 50 g/L fumaric acid production using 80 g/L glucose as carbon source, with a yield of 0.72 g/g and 0.36 g/L × h -1 productivity [12].…”

Section: Fumaric Acid Production Using Soybean Cake Hydrolysatementioning

confidence: 69%

“…Shake flasks contained 50 mL of a medium, with the following composition (g/L): glucose at initial concentration of 25 or 50; CaCO 3 , 80% of the initial carbon source concentration used in each fermentation; KH 2 PO 4 , 0.6; MgSO 4 ·7H 2 O, 0.4; ZnSO 4 ·7H 2 O, 0.044; FeCl 3 ·6H 2 O, 0.016; tartaric acid, 0.0075; corn steep liquor, 0.5 mL and methanol 15 mL [11,12]. The medium was autoclaved at 121 • C for 20 min.…”

Section: Fumaric Acid Productionmentioning

confidence: 99%

“…The dispersed mycelia of the fungus R. arrhizus has been previously cultivated in bioreactors, producing high concentrations (73-107 g/L) of fumaric acid with yields ranging from 0.72 g/g to 0.82 g/g using glucose as carbon source [6,8,26]. The small and uniform mycelial clumps led to higher fumaric acid production than compact pellets maybe due to better oxygen transfer [12].…”

Section: Effect Of Dispersed Mycelia On Fumaric Acid Productionmentioning

confidence: 99%

“…Zhang et al [12] showed that chemical hydrolysate derived from soybean meal can be utilised in the pre-culture medium of R. oryzae ATCC 20344 for fumaric acid production. Particularly, the utilisation of soybean meal hydrolysate led to 50 g/L fumaric acid production using 80 g/L glucose as carbon source, with a yield of 0.72 g/g and 0.36 g/L × h -1 productivity [12]. The fumaric acid production was improved when soybean cake hydrolysate was utilised as nitrogen source.…”

Section: Fumaric Acid Production Using Soybean Cake Hydrolysatementioning

confidence: 99%

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Biotechnological Production of Fumaric Acid: The Effect of Morphology of Rhizopus arrhizus NRRL 2582

et al. 2017

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Fumaric acid is a platform chemical with many applications in bio-based chemical and polymer production. Fungal cell morphology is an important factor that affects fumaric acid production via fermentation. In the present study, pellet and dispersed mycelia morphology of Rhizopus arrhizus NRRL 2582 was analysed using image analysis software and the impact on fumaric acid production was evaluated. Batch experiments were carried out in shake flasks using glucose as carbon source. The highest fumaric acid yield of 0.84 g/g total sugars was achieved in the case of dispersed mycelia with a final fumaric acid concentration of 19.7 g/L. The fumaric acid production was also evaluated using a nutrient rich feedstock obtained from soybean cake, as substitute of the commercial nitrogen sources. Solid state fermentation was performed in order to produce proteolytic enzymes, which were utilised for soybean cake hydrolysis. Batch fermentations were conducted using 50 g/L glucose and soybean cake hydrolysate achieving up to 33 g/L fumaric acid concentration. To the best of our knowledge the influence of R. arrhizus morphology on fumaric acid production has not been reported previously. The results indicated that dispersed clumps were more effective in fumaric acid production than pellets and renewable resources could be alternatively valorised for the biotechnological production of platform chemicals.

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Next‐generation biofuels and platform biochemicals from lignocellulosic biomass

Okolie

Mukherjee

Nanda

et al. 2021

Intl J of Energy Research

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Rapid industrialization, increasing fuel prices, exhausting fossil fuel resources and greenhouse gas emissions are some of the factors instilling the search for alternative sources of energy and chemicals. Lignocellulose biomass-derived biofuels and biochemicals have emerged as clean products to complement fossil-based resources and reduce environmental impacts. Lignocellulosic biomasses are renewable, inexpensive and abundantly available resources to produce a wide variety of liquid, gaseous and solid biofuels and industrially relevant biochemicals. Different biological (e.g., fermentation and anaerobic digestion), thermochemical (e.g., liquefaction, gasification and pyrolysis) and catalytic (e.g., transesterification) conversion technologies can be used to produce fuel and chemical products from lignocellulosic biomass. This article makes a comprehensive review of different biofuels (e.g., biodiesel, bio-oil, bioethanol, biobutanol, biogas, hydrogen, syngas and jetfuel) and value-added biochemicals (e.g., propylene, ethylene, benzene, 5-hydroxymethylfurfural, levulinic acid, succinic acid, maleic acid, fumaric acid, phenols and other aromatic compounds) from lignocellulosic biomass. Additionally, the current status, challenges and future perspectives for the production and utilization of biofuels and biochemicals are systematically discussed.

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Effects of soybean meal hydrolysate as the nitrogen source on seed culture morphology and fumaric acid production by Rhizopus oryzae

Cited by 57 publications

References 30 publications

Fumaric Acid Production: A Biorefinery Perspective

Fumaric Acid Production: A Biorefinery Perspective

Biotechnological Production of Fumaric Acid: The Effect of Morphology of Rhizopus arrhizus NRRL 2582

Next‐generation biofuels and platform biochemicals from lignocellulosic biomass

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