Effects of stannous fluoride and amine fluorides on caries incidence and enamel solubility in adults

Obersztyn, A; Kolwiński, K; Trykowski, J; Starościak, Stanisław

doi:10.1111/j.1834-7819.1979.tb03633.x

Cited by 4 publications

(6 citation statements)

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“…Across all KQs, 16 studies (in 17 publications; total 3300 participants) were included (Figure 3). One randomized clinical trial (RCT) and 7 diagnostic accuracy studies addressed screening, and 4 RCTs and 5 nonrandomized trials addressed preventive interventions. The Table summarizes the evidence reviewed for this report.…”

Section: Resultsmentioning

confidence: 99%

“…One fair-quality and 4 poor-quality trials evaluated topical fluorides (varnish or gels/solutions) vs placebo or no topical fluoride for prevention of dental caries in adults (eTables 5 and 6 in the Supplement). In all trials, topical fluorides were applied by dental professionals.…”

Section: Resultsmentioning

confidence: 99%

“…The RCT and 1 nonrandomized trial evaluated sodium fluoride varnish (22 600 ppm F). The other trials evaluated sodium fluoride (2%) solution, stannous fluoride (30%) paste followed by a stannous fluoride (10%) aqueous solution, and acidulated phosphate fluoride (1.2%) …”

Section: Resultsmentioning

confidence: 99%

“…Three trials evaluated other topical fluorides . All were nonrandomized or had unclear randomization methods.…”

Section: Resultsmentioning

confidence: 99%

“…Regarding preventive interventions, SDF solution was associated with a small decrease in the number of new root caries lesions or fillings vs placebo in older adults, but all studies were conducted in Hong Kong . Evidence for sealants (2 trials) and topical fluorides (5 trials) was insufficient, as all trials had serious methodological limitations, with inconsistency in the topical fluoride trials. The trials of preventive interventions did not evaluate periodontal or health outcomes (quality of life, function, or tooth loss) or impact on conditions associated with poor oral health, such as cardiovascular disease .…”

Section: Discussionmentioning

confidence: 99%

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Screening, Referral, Behavioral Counseling, and Preventive Interventions for Oral Health in Adults

Chou,

Selph,

Bougatsos

et al. 2023

JAMA

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ImportanceDental caries and periodontal disease are common adult oral health conditions and potentially amenable to primary care screening and prevention.ObjectiveTo systematically review the evidence on primary care screening and prevention of dental caries and periodontal disease in adults to inform the US Preventive Services Task Force.Data SourcesMEDLINE, Cochrane Central Register of Controlled Trials, and Cochrane Database of Systematic Reviews (to October 3, 2022); surveillance through July 21, 2023.Study SelectionDiagnostic accuracy studies of primary care screening instruments and oral examination; randomized and nonrandomized trials of screening and preventive interventions; cohort studies on primary care oral health screening and preventive intervention harms.Data Extraction and SynthesisOne investigator abstracted data; a second checked accuracy. Two investigators independently rated study quality. Diagnostic accuracy data were pooled using a bivariate mixed-effects binary regression model.Main Outcomes and MeasuresDental caries, periodontal disease, morbidity, quality of life, harms; and diagnostic test accuracy.ResultsFive randomized clinical trials, 5 nonrandomized trials, and 6 observational studies (total 3300 participants) were included. One poor-quality trial (n = 477) found no difference between oral health screening during pregnancy vs no screening in caries, periodontal disease, or birth outcomes. One study (n = 86) found oral health examination by 2 primary care clinicians associated with low sensitivity (0.42 and 0.56) and high specificity (0.84 and 0.87) for periodontal disease and with variable sensitivity (0.33 and 0.83) and high specificity (0.80 and 0.93) for dental caries. Four studies (n = 965) found screening questionnaires associated with a pooled sensitivity of 0.72 (95% CI, 0.57-0.83) and specificity of 0.74 (95% CI, 0.66-0.82) for periodontal disease. For preventive interventions no study evaluated primary care counseling or dental referral, and evidence from 2 poor-quality trials (n = 178) of sealants, and 1 fair-quality and 4 poor-quality trials (n = 971) of topical fluorides, was insufficient. Three fair-quality trials (n = 590) of persons with mean age 72 to 80 years found silver diamine fluoride solution associated with fewer new root caries lesions or fillings vs placebo (mean reduction, −0.33 to −1.3) and decreased likelihood of new root caries lesion (2 trials; adjusted odds ratio, 0.4 [95% CI, 0.3-0.7]). No trial evaluated primary care–administered preventive interventions.Conclusions and RelevanceScreening questionnaires were associated with moderate diagnostic accuracy for periodontal disease. Research is needed to determine benefits and harms of oral health primary care screening and preventive interventions.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

“…Three trials evaluated other topical fluorides . All were nonrandomized or had unclear randomization methods.…”

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Screening, Referral, Behavioral Counseling, and Preventive Interventions for Oral Health in Adults

Chou,

Selph,

Bougatsos

et al. 2023

JAMA

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Amine fluoride gel in a caries prophylaxis program for soldiers in Poland

Obersztyn¹,

Kolwiński²

1984

Comm Dent Oral Epid

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DMFS increments were determined in 1286 military cadets (19-20 yr old), at 6-monthly intervals during an 18-month clinical study. The cadets were randomly divided into two groups. The test group (n = 787) brushed their teeth with an amine fluoride gel for 5 min once weekly in an unsupervised manner. The control group (n = 499) as well as the test group used a fluoride-free dentifrice twice daily. In both groups, motivation in oral hygiene was given before commencing the study. The cadets in the test group had a 41% lower DMFS increment compared to the cadets in the control group.

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The Use of Topical Fluorides to Prevent Dental Caries in Adults: A Review of the Literature

Swango

1983

The Journal of the American Dental Association

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Effects of stannous fluoride and amine fluorides on caries incidence and enamel solubility in adults

Cited by 4 publications

References 0 publications

Screening, Referral, Behavioral Counseling, and Preventive Interventions for Oral Health in Adults

Screening, Referral, Behavioral Counseling, and Preventive Interventions for Oral Health in Adults

Amine fluoride gel in a caries prophylaxis program for soldiers in Poland

The Use of Topical Fluorides to Prevent Dental Caries in Adults: A Review of the Literature

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