Effects of stimulation of the subthalamic nucleus on naming and reading nouns and verbs in Parkinson's disease

The effects of subthalamic deep brain stimulation on metaphor comprehension and language abilities in Parkinson’s disease

“…In accordance with this result, studies evaluating lexical functions ON and OFF-DBS did not report any significant effect of electrical stimulation (Castner et al, 2007;Phillips et al, 2012). However, an improvement in lexico-semantic abilities was noted ON-DBS in one study (Silveri et al, 2012). Negative effects of STN stimulation were also reported on lexico-semantic capacities (Castner et al, 2008).…”

“…This deterioration was observed a few months after surgery, suggesting that this effect could be caused by the implantation of electrodes (Morrison et al, 2004). There are still few studies about the effects of bilateral STN stimulation on other language abilities and their results often seem contradictory: while a decline in syntactic, semantic, morphological and grammatical abilities was observed in some studies (Castner et al, 2008;Phillips et al, 2012;Schulz et al, 2012), others have demonstrated an improvement in syntactic and semantic abilities (Silveri et al, 2012;Zanini et al, 2003). More specifically, Whelan, Murdoch, Theodoros, Hall, and Silburn (2003) did not note any significant difference at 3 months post-surgery in metaphor comprehension in PD patients with bilateral STN-DBS.…”

Subthalamic nucleus stimulation and spontaneous language production in Parkinson’s disease: A double laterality problem

“…Some linguistic functions improved, whereas some others deteriorated with STN stimulation. These contradictory results were also found in word generation studies (Castner et al, 2008;Silveri et al, 2012) and studies examining syntactic functions (Homer, Rubin, Horowitz, & Richter, 2012;Zanini et al, 2003Zanini et al, , 2009.…”

Aspectos de comunicação oral em pacientes com doença de Parkinson submetidos à Estimulação Cerebral Profunda

“…One study evaluated action and object naming in the 'on' and 'off' DBS situations; the patients were slower and less accurate in action naming than their healthy controls. When comparing the 'on' and 'off' conditions, it was observed that the stimulation improved verb and noun naming, with greater improvement for verbs (18) .…”