Effects of Subacute Boric Acid Administration on Rat Kidney Tissue

Peng

et al. 2011

Biol Trace Elem Res

The aim of the present study was to find out the effects of boron on ostrich chicks fed with 0 mg/l, 100 mg/l, 200 mg/l, and 400 mg/l of additional boron in water. We measured bone mineral density (BMD), perimeter, length, weight, ash content of ostrich tibias, thickness of cortical bone, and diameter of the marrow cavity. We also analyzed the apoptosis status of paraffin sections using a TUNEL kit and examined serum levels of leptin and estradiol (E(2)). The results were dramatic. Compared with the control group, group C had a very high BMD. The serum levels of leptin in groups C and D were significantly higher than control values, and the levels of E(2) fluctuated. The perimeter, length, weight, and ash content of ostrich tibias all increased significantly with increasing dosage of boron. The cross-section analysis revealed that the bone marrow cavity shifted closer to one side in group D, which was observed on a macro-scale. This shift may be related to the toxicity of excessive boron, as indicated by the apoptosis status. According to the present data, additional boron was helpful for ostrich chick bone development, and 200 mg/l supplement boron in the drinking water appeared to be the most beneficial.

Section: Appropriate Amount Of Boron Brings Greatest Profitmentioning

confidence: 90%

Effect of Additional Boron on Tibias of African Ostrich Chicks

Peng

et al. 2011

Biol Trace Elem Res

American Journal of Applied Sciences

“…Therefore, with the consideration of medical purpose, the applications of boric acid should be prevented due to the potential lethality and toxicity of borates compound. Besides, explanation and awareness of its toxicity is essential because of the exposure in industrial and consumer exposure to boron (Sabuncuoglu et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

Risk and Health Effect of Boric Acid

See

Salleh

Bakar

et al. 2010

Problem statement: Boric acid is a pesticide usually used to kill mites, fungi, plants and insect including fleas, termites, cockroaches and wood decay fungi. Besides, it was also used in many fields such as food preservative, in newborn baby’s nurseries and antiseptic. Many reports indicated that boric acid poisoning occurred due to the misuse of household product and illegal use of boric acid in food product. In this study, the concern issue was the usage of boric acid that may lead to boric acid poisoning. Approach: This review had shown some information for boric acid such as its usage, the existent method for detection of boric acid in food. Besides, this review also discussed about the toxicology and pharmacokinetic of boric acid and the health impact of boric acid on human and animal. Result: Previous studies showed that food products such as yellow noodles contain boric acid. The boric acid level in most foods was different among the factory and the production period. It is due to the lack of standard measurement during the processing. Conclusion: Since boric acid was harmful to human health and may cause poisoning, hence, the control and the awareness of the usage of boric acid especially in food should be increased. There are numerous methods available for quantification of boric acid such as mannitol titration technique, colorimetric method. Accordingly, the analysis of boric acid is essential

Kafkas Univ Vet Fak Derg

“…It has both metal and nonmetal characteristics [1][2][3] . This dynamic trace element enters the body in small amounts via food and drink [4,5] . Boron can affect at least 26 different enzyme activities required for energy substrate metabolism [6,7] .…”

Section: Introductionmentioning

confidence: 99%

Geçiş Dönemi Süt İneklerinde Bazı Enerji Metabolitlerinin Üzerine Boraksın Etkisi

Öğün¹,

Merhan²,

Kükürt³

et al. 2016

The purpose of this study is to investigate the effects of sodium borate (Na2B4O7•5H2O) addition to dairy cow rations starting from prepartum period on serum cortisol, glucose, β-hydroxybutyrate (BHB), non-esterified fatty acids (NEFA), triglyceride (TG), blood urea nitrogen (BUN), aspartate aminotransferase (AST), alanine aminotransferase (ALT) levels. Clinically healthy eighty pregnant cows were randomly divided into two groups. Sodium borate (30 g/day) was added to the rations of the borax group (n=40) until day 21 postpartum. Blood samples were taken from all cows (n=40) on days 21, 14 and 7 before parturition, at parturition and on days 7, 14 and 21 after parturition. Serum cortisol levels in the borax group were lower (P<0.05) than those in the control group, there was a decrease (P<0.05) in serum BHB, NEFA and TG levels before, at parturition and after parturition, serum BUN concentrations increased (P<0.05) in prepartum and postpartum samples in the borax group, except for prepartum days 21 and 14, AST concentrations were higher (P>0.05), on all other sampling days, and ALT levels were not affected (P>0.05). It was concluded that adding sodium borate to rations especially in the transition period in highly productive dairy breeds might be an alternative to protect against negative energy imbalances.