1977
DOI: 10.1016/0044-8486(77)90211-3
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Effects of sublethal concentrations of lignosulphonates on growth, intestinal flora and some digestive enzymes of rainbow trout (Salmo gairdneri)

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Cited by 10 publications
(3 citation statements)
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“…The evidence for biological availability of immunostimulants is not overwhelming. It has been suggested that nucleotide digestion may not occur in some fishes (Roald, 1978). It may be that only the inosine monophosphate (IMP) form, not inosine, is biologically available to fishes (Ikeda et al , 1991; Kubitza et al , 1997; Li & Gatlin, 2006).…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The evidence for biological availability of immunostimulants is not overwhelming. It has been suggested that nucleotide digestion may not occur in some fishes (Roald, 1978). It may be that only the inosine monophosphate (IMP) form, not inosine, is biologically available to fishes (Ikeda et al , 1991; Kubitza et al , 1997; Li & Gatlin, 2006).…”
Section: Discussionmentioning
confidence: 99%
“…Digestion and absorption competency of exogenous nucleotides is species specific, for example, humans digest nucleotide intermediates whereas mice digest nucleosides (Sonoda & Tatibana, 1978). Research on fishes is limited mostly because nuclease, the most important enzyme for nucleotide digestion, is poorly understood, although present in rainbow trout Oncorhynchus mykiss (Walbaum 1792) (Roald, 1978). Dietary enhancement of nucleotides has caused increased growth in larval fishes (Li & Gatlin, 2006) and reduced stress in several species (Burrells et al , 2001 b ; Low et al , 2003) together with reducing the immune‐inhibiting effects of cortisol (Leonardi et al , 2003), thereby increasing disease resistance against viral, bacterial and parasitic pathogens (Li & Gatlin, 2006).…”
Section: Introductionmentioning
confidence: 99%
“…Survival was 100 percent over 28 days for concentrations up to 1,875 ppm. In a followup study, rainbow trout were subjected to sublethal concentrations of 0 (control), 40, 80, 160, and 320 ppm for 60 days and concentrations of 0, 640, 1,280, and 1,920 ppm for 35 days (Roald 1977b). Fish exposed to concentrations of 160 ppm or greater had slower growth rates than those with no exposure.…”
Section: Environmental Effects Of Dust Palliativesmentioning
confidence: 99%