Effects of Telephone Counseling Intervention by Pharmacists (TelCIP) on Medication Adherence; Results of a Cluster Randomized Trial

Kooij, Marcel J.; Heerdink, Eibert R.; Dijk, Liset van; Geffen, Erica C.G. van; Belitser, Svetlana V.; Bouvy, Marcel L.

doi:10.3389/fphar.2016.00269

Cited by 41 publications

(72 citation statements)

References 36 publications

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“…Further, patients who strongly believed that they were comfortable discussing with the pharmacist about their medicines and that they were receiving the necessary advice from them were more adherent to their antihypertensive medicines. This is consistent with several previous studies which have shown the positive impact of pharmacist intervention on adherence (Al-Jumah and Qureshi, 2012; Kooiji et al, 2016;Yasmin et al, 2016).…”

Section: Discussionsupporting

confidence: 93%

Relationship between patients’ beliefs about their antihypertensives and adherence in a secondary hospital in northern Nigeria

Labaran¹,

Mohammed²,

Saeed³

et al. 2018

Bayero J. Pure App. Sci.

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Poor adherence to medication is a major public health concern, especially in patients with hypertension because it is sometimes difficult to convince them to take medication in the absence of symptoms. The aim of this study was to assess the relationship between patients' beliefs about their antihypertensive drugs and adherence to treatment. The study was a cross-sectional study on hypertensive patients in General Hospital Katsina State. The data were collected using patient administered questionnaires. Data were analyzed using SPSS version 20.0.The study recorded a total of 127 hypertensive patients, majority of whom were females (58%) and mostly above 40 years (76%). Significant number of the respondents (98%) agreed their antihypertensives were effective in protecting them from the effects of high blood pressure. All adherent patients (100%) were strongly concerned about possible future effects of their medication, suggesting a high counterbalancing effect of this belief on their adherence. Majority (77%) believed they were receiving the necessary advice about their medicines from the pharmacist. Overall adherence to treatment was excellent (80%). A statistically significant relationship (p<.05) was established between patient's beliefs and adherence. In conclusion, the study revealed that adherence to antihypertensive medication is attributed to patients' beliefs and the role of pharmacists cannot be overemphasized.

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Section: Discussionsupporting

confidence: 93%

Relationship between patients’ beliefs about their antihypertensives and adherence in a secondary hospital in northern Nigeria

Labaran¹,

Mohammed²,

Saeed³

et al. 2018

Bayero J. Pure App. Sci.

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“…For example, among US age-qualified Medicare part D beneficiaries who were enrolled in stand-alone prescription drug plans (PDPs) from 2007 to 2008 and were prescribed statins, the proportion of people who were nonadherent at one year was 31.5% [33]. Similarly, among older Finnish people prescribed statins, just 13% had discontinued at one year [34], whereas a study based on a cohort of older adults from the Netherlands reported one-year statin discontinuation of <30% [35]. Overall, taken together with prior research [5], our results support the need for multifaceted interventions to improve statin adherence among older people [36].…”

Section: Factors Associated With Statin Nonadherence and Discontinuationmentioning

confidence: 99%

Predictors of first‐year nonadherence and discontinuation of statins among older adults: a retrospective cohort study

Ofori‐Asenso

Ilomäki

Tacey

et al. 2018

Brit J Clinical Pharma

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Aims The aim of this study was to examine the level of and predictors of statin nonadherence and discontinuation among older adults. Methods Among 22 340 Australians aged ≥65 years who initiated statin therapy from January 2014 to December 2015, we estimated the first‐year nonadherence (proportion of days covered [PDC] <0.80) and discontinuation (≥90 days without statin coverage) rates. Predictors of nonadherence and discontinuation were examined via multivariable logistic regression. Analyses were performed separately for general beneficiaries (with a higher co‐payment; n = 4841) and concessional beneficiaries (with a lower co‐payment; n = 17 499). Results During the one‐year follow‐up, 55.1% were nonadherent (concessional 52.6%; general beneficiaries 64.2%) and 44.7% discontinued statins (concessional 43.1%; general beneficiaries 50.4%). Among concessional beneficiaries, those aged 75–84 years and ≥85 years were more likely to discontinue than people aged 65–74 years (odds ratio 1.11, 95% confidence interval 1.04–1.19 and 1.38, 1.23–1.54, respectively). Diabetes was associated with an increased likelihood of nonadherence and discontinuation, while hypertension, angina and congestive heart failure were associated with a lower likelihood of nonadherence and discontinuation. Anxiety was associated with an increased likelihood of discontinuation, but polypharmacy (concurrent use of five or more drugs) was associated with a lower likelihood of nonadherence and discontinuation. Statin initiation by a general medical practitioner was associated with both increased likelihood of nonadherence and discontinuation. Similar predictors of nonadherence and discontinuation were identified for the general beneficiaries. Conclusions Among older adults prescribed statins, first‐year nonadherence and discontinuation are high. Specific population subgroups such as people aged ≥85 years, those with diabetes or anxiety may require additional attention to improve statin adherence.

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“…Since the establishment of the system of clinical pharmacists in China in 2002, clinical pharmacists have been increasingly involved in ASPs in hospitals (Xiao and Li, 2013;Li et al, 2017;Zhang et al, 2017). Pharmacist-led interventions have yielded excellent results in many areas (Kooij et al, 2016;van Eikenhorst et al, 2017;Ravn-Nielsen et al, 2018;van der Laan et al, 2018). However, the studies that have been performed on ASPs for hospital inpatients led by pharmacists have received insufficient attention in developing countries (Davey et al, 2017;Sakeena et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

Impact of a Multifaceted Pharmacist-Led Intervention on Antimicrobial Stewardship in a Gastroenterology Ward: A Segmented Regression Analysis

Wang

et al. 2020

Front. Pharmacol.

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Background: Irrational use of antimicrobial agents for gastrointestinal diseases deserves attention, but corresponding antimicrobial stewardship programs (ASPs) are generally not a priority for managers. We conducted this study to evaluate the effectiveness of multifaceted pharmacist-led (MPL) interventions in the gastroenterology ward (GW) to provide evidence for the efficacy of ASPs in a non-priority department. Methods: This was an interventional, retrospective study implemented in China. The MPL intervention lasting 1.5 years involved daily ward rounds with physicians, regular review of medical orders, monthly indicator feedback, frequent physician training, and necessary patient education. Data on all hospitalized adults receiving antibiotics was extracted from the hospital information system over a 36-month period from January 2016 to December 2018. Segmented regression analysis of interrupted time series was performed to evaluate the effect of the MPL interventions (started in July 2017) on antibiotic use and length of hospital stay, which was calculated monthly as analytical units. Results: A total of 1763 patients receiving antibiotics were enrolled. Segmented regression models showed descending trends from the baseline in the intensity of antibiotic consumption (coefficient = −0.88, p = 0.01), including a significant decline in the level of change of the proportion of patients receiving combined antibiotics (coefficient = −9.91, p = 0.03) and average length of hospital stay (coefficient = −1.79, p = 0.00), after MPL interventions. The MPL interventions led to a temporary increase in the proportion of patients receiving antibiotics (coefficient = 4.95, p = 0.038), but this was part of a declining secular trend (coefficient = −0.45, p = 0.05). Conclusion: The MPL interventions led a statistically significant decline in the number of patients receiving antibiotics, the antibiotic consumption, and the average hospital stay post-intervention compared to the pre-intervention phase of the study. Health

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Effects of Telephone Counseling Intervention by Pharmacists (TelCIP) on Medication Adherence; Results of a Cluster Randomized Trial

Cited by 41 publications

References 36 publications

Relationship between patients’ beliefs about their antihypertensives and adherence in a secondary hospital in northern Nigeria

Relationship between patients’ beliefs about their antihypertensives and adherence in a secondary hospital in northern Nigeria

Predictors of first‐year nonadherence and discontinuation of statins among older adults: a retrospective cohort study

Impact of a Multifaceted Pharmacist-Led Intervention on Antimicrobial Stewardship in a Gastroenterology Ward: A Segmented Regression Analysis

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