Effects of the attenuation correction and reconstruction method parameters on conventional cardiac dynamic SPECT

Mohseni, Mohammadreza; Faghihi, Reza; Haghighatafshar, Mahdi; Entezarmahdi, Seyed Mohammad

doi:10.1097/md.0000000000012239

Cited by 1 publication

(1 citation statement)

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“…Note that with G-SPECT-I, overhead time is introduced by the bed translations required to scan volumes larger than the CDV, while for traditional SPECT overhead time is associated with the need to rotate the heads. For traditional scanners with step-and-shoot mode, 64 or 128 views are generally required for sufficient angular sampling (even for a small scanning volume), which results in more than 20 detector stops even for a triple-head system leading to an overhead time of 40-80 s assuming 2-4 s movement time per view, as reported in (Cao et al 1996, Mohseni et al 2018. Instead, the G-SPECT-I design with stationary detectors offers the flexibility of performing focused scans where only few bed translations are required while also allowing for extended volume scans.…”

Section: Discussionmentioning

confidence: 99%

Optimized sampling for high resolution multi-pinhole brain SPECT with stationary detectors

Chen¹,

Goorden²,

Vastenhouw³

et al. 2020

Phys. Med. Biol.

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Brain perfusion SPECT can be used in the diagnosis of various neurologic or psychiatric disorders, e.g. stroke, epilepsy, dementia and posttraumatic stress disorder. As traditional SPECT provides limited resolution and sensitivity, we recently proposed a high resolution focusing multi-pinhole clinical SPECT scanner dubbed G-SPECT-I (Beekman et al 2015). G-SPECT-I achieves data completeness in the scan region of interest by making small translations of the patient bed while using projections from all bed positions together for image reconstruction. A strategy to restrict the number of bed translations is desired to minimize overhead time. Previously we presented optimized bed translation paths for focused partial brain imaging, while here we focus on whole brain imaging which is the common procedure in perfusion studies. Thus, a series of noise-free scans using a reduced number of bed positions were simulated and compared to an oversampled reference scan acquired with 128 bed positions. Noisy simulations were included to validate the utility of the optimized sequences in more realistic situations. Brain Uptake Ratios (BURs) and left-right Asymmetry Indices (AIs) in 51 selected Regions of Interest (ROIs) were calculated for assessment. Results show that images were barely affected by decreasing the number of bed positions from 128 down to 18 (mean deviation from the reference of only 2.2% and 1.5% for the BUR and AI respectively) while slightly larger deviations (2.9% and 2.7% respectively) were obtained when using 12 positions. For both 18-and 12-position sequences these deviations due to sampling were much smaller than those induced by noise (mean deviation of 6.5% and 8.6% respectively). Given an associated total overhead for bed movement of half a minute (18 positions) or 20 seconds (12 positions), G-SPECT-I can be a clinical platform that brings new protocols for fast (dynamic) whole brain SPECT and motion correction into reach.

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Section: Discussionmentioning

confidence: 99%